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Note 6 - Significant Agreements and Contracts (Details Textual) $ in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Jun. 30, 2024 | Feb. 29, 2024 USN ($) | Aug. 31, 2014 USD ($) | Sep. 30, 2024 USD ($) | Sep. 30, 2023 USD ($) | Sep. 30, 2024 USD ($) | Sep. 30, 2023 USD ($) | Dec. 31, 2025 USD ($) | Dec. 31, 2024 USD ($) | Dec. 31, 2023 USD ($) | Aug. 31, 2024 USD ($) | Jan. 31, 2023 USD ($) | Jan. 01, 2023 USN ($)
Research and Development Expense |  |  |  | $ 5,125,097 | $ 1,791,487 | $ 11,711,746 | $ 5,583,149 |  |  |  |  |  |
Revenues |  |  |  | 1,939,751 | 1,526,482 | 7,575,972 | 4,654,294 |  |  |  |  |  |
Vertex Option and License Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Research and Development Expense |  |  | $ 100,000 |  |  |  |  |  |  |  |  |  |
Contractual Obligation |  |  |  |  | 117,000,000 |  | 117,000,000 |  |  |  |  |  |
Payments for License Agreement |  |  | $ 100,000 |  |  |  |  |  |  |  |  |  |
National Institute of Aging Grant [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Government Assistance, Asset |  |  |  |  |  |  |  |  |  |  | $ 300,000 | $ 21,000,000 | $ 21.3
Government Assistance, Income, Increase (Decrease) |  | $ 7.3 |  |  |  |  |  |  |  | $ 6,700,000 |  |  |
Revenues |  |  |  | 1,900,000 | $ 1,500,000 | 7,600,000 | $ 4,700,000 |  |  |  |  |  |
Proceeds From Grants |  |  |  |  |  | 14,500,000 |  |  |  |  |  |  |
Grant Funding Remaining |  |  |  | $ 6,800,000 |  | $ 6,800,000 |  |  |  |  |  |  |
Grant Amount, Received, Parentage | 10.00% | 90.00% |  |  |  |  |  |  |  |  |  |  |
National Institute of Aging Grant [Member] | Forecast [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Government Assistance, Income, Increase (Decrease) |  |  |  |  |  |  |  | $ 6,200,000 | $ 8,400,000 |  |  |  |

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