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Note 6 - Significant Agreements and Contracts (Details Textual) - USD ($) | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | ---
Mar. 31, 2025 | Aug. 31, 2014 | Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023 | Aug. 31, 2024 | Jan. 31, 2023
Research and Development Expense |  |  |  | $ 18,798,343 | $ 8,438,499 |  |
Government Assistance, Asset |  |  |  | 21,300,000 |  |  |
Revenues |  |  |  | 9,737,974 | 7,144,872 |  |
Vertex Option and License Agreement [Member] |  |  |  |  |  |  |
Research and Development Expense |  | $ 100,000 |  |  |  |  |
Contractual Obligation |  | 117,000,000 |  |  |  |  |
Payments for License Agreement |  | $ 100,000 |  | 0 | 0 |  |
National Institute of Aging Grant [Member] |  |  |  |  |  |  |
Government Assistance, Asset |  |  |  |  |  | $ 300,000 | $ 21,000,000
Government Assistance, Income, Increase (Decrease) | $ 5,600,000 |  |  | 8,300,000 | 6,700,000 |  |
Revenues |  |  |  | 9,700,000 | $ 7,100,000 |  |
Proceeds From Grants |  |  |  | 14,600,000 |  |  |
Grant Funding Remaining |  |  |  | 6,600,000 |  |  |
Deferred Revenue, Current |  |  |  | $ 2,300,000 |  |  |
Grant Amount, Received, Parentage | 90.00% |  |  |  |  |  |
National Institute of Aging Grant [Member] | Forecast [Member] |  |  |  |  |  |  |
Government Assistance, Income, Increase (Decrease) |  |  | $ 6,200,000 |  |  |  |

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