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Note 3 - Summary of Significant Accounting Policies (Tables)
9 Months Ended
Sep. 30, 2025
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   

September 30,

 
   

2025

   

2024

 

Common stock warrants

    2,601,671       2,633,868  

Stock options

    995,374       533,159  
      3,597,045       3,167,027  
Schedule of Segment Reporting Information, by Segment [Table Text Block]

 

   

Three Months Ended

September 30,

   

Nine Months Ended

September 30,

 
   

2025

   

2024

   

2025

   

2024

 

Grant revenue

  $ 322,569     $ 1,939,751     $ 3,997,784     $ 7,575,972  

Research and development expenses:

                               

Dementia with Lewy bodies

    1,680,922       3,317,345       5,866,430       8,753,991  

Frontotemporal dementia

    313,438       2,581       846,664       2,581  

Recovery after stroke

    396,635       112,759       952,338       112,759  

Other clinical* and preclinical

    485,586       541,125       1,505,726       542,932  

Personnel costs, excluding stock-based compensation

    1,767,086       643,024       4,060,722       1,235,556  

Stock-based compensation

    133,169       42,224       378,029       146,358  

Other research and development expenses, including CMC**

    1,263,606       466,039       2,376,956       917,569  

Total research and development expenses

    6,040,442       5,125,097       15,986,865       11,711,746  

General and administrative expenses:

                               

Personnel costs, excluding stock-based compensation

    1,087,467       1,168,151       3,797,765       2,968,276  

Stock-based compensation

    158,548       22,050       771,869       921,653  

Professional fees

    711,307       707,725       2,053,984       2,049,828  

Insurance, taxes and similar fees

    258,032       241,123       917,616       709,178  

Other general and administrative expenses, including IT, facilities, supplies and similar costs***

    110,972       71,878       433,043       201,601  

Total general and administrative expenses

    2,326,326       2,210,927       7,974,277       6,850,536  

Other income

    317,560       642,732       1,084,281       1,401,529  

Net loss

  $ (7,726,639 )   $ (4,753,541 )   $ (18,879,077 )   $ (9,584,781 )