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Note 3 - Summary of Significant Accounting Policies - Schedule of Segment Information (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Grant revenue $ 322,569 $ 1,939,751 $ 3,997,784 $ 7,575,972
Research and development expense 6,040,442 5,125,097 15,986,865 11,711,746
Stock-based compensation 291,717 271,215 1,149,899 1,068,011
Total general and administrative expenses 2,326,326 2,210,927 7,974,277 6,850,536
Other income 317,560 642,732 1,084,281 1,401,529
Net loss (7,726,639) (4,753,541) (18,879,077) (9,584,781)
Operating Segments [Member]        
Grant revenue 322,569 1,939,751 3,997,784 7,575,972
Research and development expense 6,040,442 5,125,097 15,986,865 11,711,746
Personnel costs, excluding stock-based compensation 1,087,467 1,168,151 3,797,765 2,968,276
Stock-based compensation 158,548 22,050 771,869 921,653
Professional fees 711,307 707,725 2,053,984 2,049,828
Insurance, taxes and similar fees 258,032 241,123 917,616 709,178
Other general and administrative expenses, including IT, facilities, supplies and similar costs [1] 110,972 71,878 433,043 201,601
Total general and administrative expenses 2,326,326 2,210,927 7,974,277 6,850,536
Other income 317,560 642,732 1,084,281 1,401,529
Net loss (7,726,639) (4,753,541) (18,879,077) (9,584,781)
Operating Segments [Member] | Dementia with Lewy bodies [Member]        
Research and development expense 1,680,922 3,317,345 5,866,430 8,753,991
Operating Segments [Member] | Frontotemporal Dementia [Member]        
Research and development expense 313,438 2,581 846,664 2,581
Operating Segments [Member] | Recovery After Stroke [Member]        
Research and development expense 396,635 112,759 952,338 112,759
Operating Segments [Member] | Other Clinical and Nonclinical [Member]        
Research and development expense 485,586 541,125 1,505,726 542,932
Operating Segments [Member] | Personnel Costs [Member]        
Research and development expense 1,767,086 643,024 4,060,722 1,235,556
Operating Segments [Member] | Stock Based Compensation [Member]        
Research and development expense 133,169 42,224 378,029 146,358
Operating Segments [Member] | Other Research and Development Costs [Member]        
Research and development expense [2] $ 1,263,606 $ 466,039 $ 2,376,956 $ 917,569
[1] Includes, among other things, costs related to IT systems, rent and other facilities, office supplies, and similar costs
[2] Includes, among other things, CMC-related costs, shipping, packaging and storage costs, certain consulting costs, and other miscellaneous research development expenses.