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Note 10 - Stock-based Compensation Expense - Stock Option Activity (Details)
$ / shares in Units, $ in Thousands
 9 Months Ended 12 Months Ended
Sep. 30, 2025
USD ($)
$ / shares
shares
Dec. 31, 2024
$ / shares
shares
Balance, number of shares (in shares) | shares 636,802  
Balance, weighted average exercise price (in dollars per share) | $ / shares $ 19.38  
Balance, weighted average remaining contractual term (Year) 7 years 1 month 6 days 7 years 7 months 6 days
Granted, number of shares (in shares) | shares 375,400  
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 3.63  
Expired, number of shares (in shares) | shares (16,828)  
Expired, weighted average exercise price (in dollars per share) | $ / shares $ 60.14  
Outstanding, shares (in shares) | shares 995,374 636,802
Outstanding, weighted average exercise price per share (in dollars per share) | $ / shares $ 12.75 $ 19.38
Outstanding, aggregate intrinsic value | $ $ 0  
Exercisable, shares (in shares) | shares 536,826  
Exercisable, weighted average exercise price per share (in dollars per share) | $ / shares $ 18.38  
Exercisable, weighted average remaining contractual term (Year) 5 years 10 months 24 days  
Exercisable, aggregate intrinsic value | $ $ 0