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Note 12 - Segments (Tables)
12 Months Ended
Dec. 31, 2025
Notes Tables  
Schedule of Segment Reporting Information, by Segment [Table Text Block]
   

Year Ended

December 31,

 
   

2025

   

2024

 

Grant revenue

  $ 4,006,510     $ 9,737,974  

Research and development expenses:

               

Dementia with Lewy bodies

    7,052,512       12,102,842  

Frontotemporal disorders (incl. nfvPPA)

    1,217,784       36,853  

Recovery after stroke

    1,427,966       391,659  

Other clinical* and nonclinical

    2,504,863       2,499,202  

Personnel costs, excluding stock-based compensation

    5,745,558       2,187,221  

Stock-based compensation

    482,669       218,822  

Other research and development expenses, including CMC**

    3,385,720       1,361,744  

Total research and development expenses

    21,817,072       18,798,343  

General and administrative expenses:

               

Personnel costs, excluding stock-based compensation

    4,988,705       3,995,114  

Stock-based compensation

    965,965       1,186,900  

Professional fees

    2,752,710       2,684,386  

Insurance, taxes and similar fees

    1,166,374       985,481  

Other general and administrative expenses, including IT, facilities, supplies and similar costs***

    610,561       314,879  

Total general and administrative expenses

    10,484,315       9,166,760  

Other income

    1,328,510       1,936,436  

Net loss

  $ (26,966,367 )   $ (16,290,693 )