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Note 11 - Income Taxes - Rate Reconciliation of Income Tax Rate (Details) - USD ($)		12 Months Ended
		Dec. 31, 2025		Dec. 31, 2024
Federal tax benefit at statutory rate		21.00%		21.00%
US Federal statutory tax rate		$ 5,671,648
State tax, net of federal benefit		0.00%	[1]	4.40%
State and local income tax, net of federal (national) income tax effect (a)	[1]	$ 0
Research and development credits		4.20%		3.20%
Tax credits		$ 1,121,821
Tax credits		(4.20%)
Change in valuation allowance		(22.90%)		(27.30%)
Changes in valuation allowances		$ 6,188,171
Share-based compensation		0.00%		(1.10%)
Nontaxable or nondeductible items		$ 605,298
Nontaxable or nondeductible items		(2.30%)
Other		(2.30%)		(0.20%)
Total provision		$ 0
Total provision		0.00%		0.00%
[1] State taxes in Illinois and Massachusetts made up the majority of the tax effect in this category

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