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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Revenue:    
Collaboration agreements $ 135  
Operating expenses:    
Research and development, net of tax credits 40,091 $ 20,995
General and administrative 14,346 5,382
Total operating expenses 54,437 26,377
Loss from operations (54,302) (26,377)
Other (expense) income, net    
Realized and unrealized (loss) gain on foreign exchange (664) 712
Change in fair value of Series A Preferred Share tranche obligation   (1,350)
Interest income 240  
Other expense (16) (6)
Total other expense, net (440) (644)
Loss before income taxes (54,742) (27,021)
Income tax benefit (expense) 1,325 (195)
Net loss and comprehensive loss (53,417) (27,216)
Net loss attributable to common shareholders—basic and diluted $ (53,417) $ (27,216)
Net loss per share attributable to common shareholders—basic and diluted $ (2.66) $ (17.81)
Weighted-average common shares outstanding—basic and diluted 20,045,602 1,528,374