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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash Flows From Operating Activities:    
Net loss and comprehensive loss for the period $ (21,417) $ (12,601)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 2,057 271
Depreciation expense 322 196
Non-cash lease expense 371 155
Foreign exchange (gain) loss (41) 1,772
Amortization of premiums on marketable securities 29  
Deferred tax (174)  
Changes in operating assets and liabilities:    
Prepaid expenses 2,796 (56)
Research and development tax credits receivable (238) (191)
Other receivables 1,017 (400)
Other non-current assets   (713)
Accounts payable 1,201 1,187
Accrued expenses and other current liabilities 253 758
Operating lease liability, current portion (135) 16
Income tax payable 12 53
Operating lease liability, net of current portion (114) (164)
Deferred revenue (166)  
Net cash used in operating activities (14,227) (9,717)
Cash Flows From Investing Activities:    
Purchases of property and equipment (772) (30)
Net cash used in investing activities (772) (30)
Cash Flows From Financing Activities:    
Proceeds from exercise of stock options 183 324
Payment of deferred offering costs   (102)
Net cash provided by financing activities 183 222
Effect of exchange rate fluctuations on cash held 34 (1,577)
Net Decrease In Cash And Cash Equivalents And Restricted Cash (14,782) (11,102)
Cash and cash equivalents and restricted cash at beginning of period 326,396 95,005
Cash and cash equivalents and restricted cash at end of period 311,614 83,903
Reconciliation Of Cash And Cash Equivalents And Restricted Cash    
Cash and cash equivalents 311,399 83,711
Restricted cash 215 192
Total cash and cash equivalents and restricted cash 311,614 83,903
Supplemental Disclosure Of Cash Flow Information:    
Property and equipment purchases in accounts payable and accrued expenses and other current liabilities $ 286 7
Deferred offering costs in accrued expenses   $ 1,084