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Income Taxes - Summary of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020
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Income Tax Disclosure [Abstract] |  |
Net operating loss carryforwards | $ 30,093 | $ 5,087
Net research and development expenditures | 10,656 | 7,478
Share issuance costs | 3,538 | 4,506
Net federal investment tax credits | 4,805 | 3,181
U.S. research and development tax credits | 1,775 | 961
Tax basis of property and equipment in excess of carrying values |  | (86)
Operating lease right-of-use assets | (1,995) | (1,240)
Operating lease liability | 1,950 | 1,063
Accrued expense and other liabilities | 760 | 345
Deferred revenue | 13,656 | 15,372
Share-based compensation | 988 | 103
Total deferred tax assets | 66,226 | 36,770
Valuation allowance | (62,606) | (35,358)
Net deferred tax assets | $ 3,620 | $ 1,412

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