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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Cash Flows From Operating Activities:      
Net loss and comprehensive loss for the year $ (106,908) $ (53,417) $ (27,216)
Adjustments to reconcile net loss to net cash used in operating activities:      
Share-based compensation expense 12,829 2,537 511
Depreciation expense 1,471 897 605
Change in fair value of Series A Preferred Shares tranche obligation     1,350
Non-cash lease expense 1,873 890 362
Loss on disposal of property and equipment 24    
Foreign exchange loss (gain) 12 588 (629)
Amortization of premiums on marketable securities 113    
Deferred tax asset (2,208) (1,280)  
Changes in operating assets and liabilities:      
Prepaid expenses (32) (6,988) (466)
Research and development tax credits receivable (556) (909) (566)
Other receivables 3,554 (2,038) (1,347)
Other non-current assets (298) 71 (464)
Accounts payable 152 17 833
Accrued expenses and other current liabilities 11,166 4,573 611
Operating lease liability, current portion 98 (225) 21
Income tax payable 505 (200) 218
Operating lease liability, net of current portion (1,118) (465) (394)
Deferred revenue (6,473) 49,865 8,142
Net cash used in operating activities (85,796) (6,084) (18,429)
Cash Flows From Investing Activities:      
Purchase of property and equipment (1,690) (2,237) (1,304)
Proceeds on disposal of property and equipment 40    
Proceeds from maturities of marketable securities 7,450    
Purchase of marketable securities (7,476) (7,526)  
Net cash used in investing activities (1,676) (9,763) (1,304)
Cash Flows From Financing Activities:      
Proceeds from exercise of stock options 986 799  
Proceeds from issuance of common stock under the 2020 Employee Share Purchase Plan 283    
Net proceeds from issuance of common shares in follow-on offering 94,288    
Proceeds from issuance of warrant   15,000  
Net proceeds from issuance of common shares in initial public offering   232,043  
Net cash provided by financing activities 95,557 247,842 103,243
Effect of exchange rate fluctuations on cash held (54) (604) 566
Net Increase In Cash And Cash Equivalents And Restricted Cash 8,031 231,391 84,076
Cash and cash equivalents and restricted cash at beginning of year 326,396 95,005 10,929
Cash and cash equivalents and restricted cash at end of year 334,427 326,396 95,005
Reconciliation Of Cash And Cash Equivalents And Restricted Cash      
Cash and cash equivalents 334,427 326,184 94,797
Restricted cash   212 208
Total cash and cash equivalents and restricted cash 334,427 326,396 95,005
Supplemental Disclosure Of Cash Flow Information:      
Cash interest received 240 216  
Cash taxes paid, net 25 156 23
Property and equipment purchases incurred but not yet paid 1,719 218 40
Right-of-use assets obtained in exchange for new operating lease liability $ 4,690 4,538 1,074
Conversion of Series A and B Preferred Shares into common shares   135,997  
Conversion of warrant into common shares   $ 15,000  
Series A Preferred Shares      
Cash Flows From Financing Activities:      
Proceeds from issuance of Preferred Shares, net     20,995
Series B Preferred Shares      
Cash Flows From Financing Activities:      
Proceeds from issuance of Preferred Shares, net     $ 82,248