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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Revenue:        
Collaboration agreements $ 30,249 $ 679 $ 35,927 $ 1,087
Operating expenses:        
Research and development, net of tax credits 33,788 31,475 65,618 57,933
General and administrative 8,719 7,938 17,248 16,717
Total operating expenses 42,507 39,413 82,866 74,650
Loss from operations (12,258) (38,734) (46,939) (73,563)
Other income (expense), net        
Realized and unrealized (loss) gain on foreign exchange (41) 141 (97) 124
Interest income 3,489 544 6,916 673
Other expense (26) (11) (41) (19)
Total other income, net 3,422 674 6,778 778
Loss before income taxes (8,836) (38,060) (40,161) (72,785)
Income tax expense (3,110) (33) (6,726) (65)
Net loss (11,946) (38,093) (46,887) (72,850)
Unrealized (loss) gain on available-for-sale marketable securities (189) 0 4 0
Total other comprehensive (loss) gain (189) 0 4 0
Comprehensive loss $ (12,135) $ (38,093) $ (46,883) $ (72,850)
Net loss per share attributable to common shareholders--basic $ (0.28) $ (0.91) $ (1.11) $ (1.74)
Net loss per share attributable to common shareholders--diluted $ (0.28) $ (0.91) $ (1.11) $ (1.74)
Weighted-average common shares outstanding-basic 42,089,530 41,899,509 42,065,237 41,880,666
Weighted-average common shares outstanding-diluted 42,089,530 41,899,509 42,065,237 41,880,666