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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash Flows From Operating Activities:    
Net loss for the period $ (46,887) $ (72,850)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation expense 12,327 9,500
Depreciation expense 947 1,039
Non-cash lease expense 1,086 1,091
Foreign exchange loss (gain) 60 (136)
Net (accretion)/amortization of marketable securities (3,928) 34
Deferred tax 0 (2,609)
Changes in operating assets and liabilities:    
Prepaid expenses 1,518 3,072
Other current receivables (988) (389)
Other non-current assets 89 89
Accounts payable 4,429 2,698
Accrued expenses and other current liabilities (17) 3,334
Operating lease liability, current portion 72 460
Income taxes (2,991) (1,322)
Operating lease liability, net of current portion (1,172) (1,123)
Deferred revenue (30,677) (1,087)
Net cash used in operating activities (66,132) (58,199)
Cash Flows From Investing Activities:    
Purchases of property and equipment (1,540) (2,056)
Proceeds from maturities of marketable securities 169,000 5,150
Purchase of marketable securities (145,796) (4,000)
Net cash provided by (used in) investing activities 21,664 (906)
Cash Flows From Financing Activities:    
Proceeds from exercise of stock options 44 233
Proceeds from issuance of common stock under the 2020 Employee Share Purchase Plan 409 213
Net cash provided by financing activities 453 446
Effect of exchange rate fluctuations on cash held 38 66
Net Decrease In Cash And Cash Equivalents (43,977) (58,593)
Cash and cash equivalents at beginning of period 159,521 334,427
Cash and cash equivalents at end of period 115,544 275,834
Supplemental Disclosure Of Cash Flow Information:    
Property and equipment purchases incurred but not yet paid 0 222
Right-of-use asset obtained in exchange for new operating lease liability $ 149 $ 56