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Stock-Based Compensation (Tables) | 3 Months Ended | 12 Months Ended
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Mar. 31, 2017 | Dec. 31, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |  |
Schedule of Stock Option Activity | A summary of all stock option activity at and for the three months ended March 31, 2017 is presented below:
|  | # of Options |  |  | Weighted- Average Exercise Price |
Outstanding at December 31, 2016 |  |  | 173,750 |  |  | $ | 9.24 |
Options granted |  |  | 111,667 | (1) |  |  | 4.71 |
Options exercised |  |  | - |  |  |  | - |
Options canceled |  |  | - |  |  |  | - |
Outstanding at March 31, 2017 |  |  | 285,417 |  |  | $ | 7.47 |
Exercisable at March 31, 2017 |  |  | 86,285 |  |  | $ | 11.79 |
(1) options granted under 2016 Stock Incentive Plan; | A summary of all stock option activity at and for the years ended December 31, 2016 and 2015 is presented below:
|  | # of Options |  |  | Weighted- Average Exercise Price |
Outstanding at December 31, 2014 |  |  | 16,667 | (1) |  | $ | 24.00 |
Options granted |  |  | 27,500 | (2) |  |  | 69.60 |
Options exercised |  |  | - |  |  |  | - |
Options canceled |  |  | (7,500 | )(2) |  |  | 120.00 |
Outstanding at December 31, 2015 |  |  | 36,667 |  |  | $ | 38.40 |
Options granted |  |  | 142,500 | (3) |  |  | 5.49 |
Options exercised |  |  | - |  |  |  | - |
Options canceled |  |  | (5,417 | )(3) |  |  | 108.69 |
Outstanding at December 31, 2016 |  |  | 173,750 |  |  | $ | 9.24 |
Exercisable at December 31, 2016 |  |  | 48,325 |  |  | $ | 14.31 |
(1) Non-Plan options. (2) 27,500 options granted under 2015 Stock Incentive Plan; 7,500 non-plan options, which were subsequently canceled under an agreement with the holder. (3) 142,500 options granted under 2016 Equity Incentive Plan; 5,417 options were canceled under the 2015 Stock Incentive Plan.
Schedule of Weighted-Average Assumptions Used in the Black-scholes Valuation Model Options |  | The following weighted-average assumptions were used in the Black-Scholes valuation model for options granted during the year ended December 31, 2016:
Risk-free interest rate |  |  | 1.17 | %
Expected term (in years) |  |  | 3.38 |
Dividend yield |  |  | - |
Expected volatility |  |  | 75 | %

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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of employee stock purchase plans, including, but not limited to: (a) expected term, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
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