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Stockholders' Equity - Narrative (Detail) - USD ($)
 3 Months Ended 12 Months Ended
Jan. 01, 2022
Feb. 16, 2021
Mar. 31, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Class of Stock [Line Items]            
Common stock, shares authorized (in shares)       1,000,000,000 1,000,000,000  
Common stock, par value (in dollars per share)       $ 0.0001 $ 0.0001  
Preferred stock, shares authorized (in shares)       10,000,000 10,000,000  
Common stock, voting rights       one    
Common stock, shares outstanding (in shares)       143,034,225 141,301,569  
Sponsor vesting shares outstanding (in shares)       4,500,000 4,500,000  
Stock option plan, exercisable period       10 years    
Common stock, shares reserved (in shares)       27,846,011    
Stock options available for grant (in shares)       15,728,837 11,285,104  
Stock options, exercisable (in shares)       3,588,523 4,130,184  
Total intrinsic value of options exercised       $ 8,500,000 $ 300,000  
Stock option, aggregate intrinsic value       28,700,000 49,300,000  
Nonvested award, cost not yet recognized       4,700,000 6,600,000  
Stock-based compensation       7,235,000 5,767,000 $ 1,630,000
Stock compensation not yet recognized       $ 27,000,000    
Non employee            
Class of Stock [Line Items]            
Stock option plan, exercisable period       4 years    
General and administrative expense            
Class of Stock [Line Items]            
Stock-based compensation       $ 4,700,000 4,500,000 1,600,000
Research and development expense            
Class of Stock [Line Items]            
Stock-based compensation       $ 2,500,000 1,300,000 $ 100,000
Performance and market based awards            
Class of Stock [Line Items]            
Stock options issued during the period (in shares)           2,920,732
Stock options, vested (in shares)   529,119        
Stock-based compensation         $ 2,900,000  
Performance and market based awards | First vesting            
Class of Stock [Line Items]            
Stock option plan, vesting percentage     2.0833%      
Stock options, outstanding (in shares)     529,119      
Performance and market based awards | Second vesting            
Class of Stock [Line Items]            
Stock options, outstanding (in shares)     2,391,613      
Restricted stock units (RSUs)            
Class of Stock [Line Items]            
Vesting period       2 years 8 months 12 days    
Service period       3 years    
Restricted stock units (RSUs) | Tranche one            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       33.30%    
Restricted stock units (RSUs) | Tranche two            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       33.30%    
Restricted stock units (RSUs) | Tranche three            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       33.30%    
Stock Options            
Class of Stock [Line Items]            
Vesting period       1 year 8 months 1 day    
Stock compensation not yet recognized, vesting period       1 year 8 months 12 days 2 years 7 months 6 days  
Stock options issued during the period (in shares)       0 0  
Performance shares            
Class of Stock [Line Items]            
Fair value of shares vested       $ 3,600,000 $ 0  
Stock-based compensation       $ 2,800,000    
Unvested outstanding (in shares)       2,218,925    
One year from the vesting commencement date            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       25.00%    
Vesting period       1 year    
Employee Stock Purchase Plan (ESPP) | Employee stock            
Class of Stock [Line Items]            
Purchase price of common stock, percent       85.00%    
Number of shares authorized (in shares)       3,722,490 1,846,710  
Evergreen shares reserve feature period       10 years    
Percentage of fully diluted shares of common stock       1.00%    
Increase in number of shares of authorized common stock (in shares)       3,693,420    
Number of additional shares authorized (in shares)       1,875,780    
Stock Incentive Plan | More than one year from vesting commencement date            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       2.778%    
The Stock Plans | Performance shares | Minimum            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       0.00%    
The Stock Plans | Performance shares | Maximum            
Class of Stock [Line Items]            
Stock option plan, vesting percentage       300.00%    
Twenty Twenty One Equity Incentive Plan | Employee stock            
Class of Stock [Line Items]            
Number of shares authorized (in shares)         18,467,109  
Evergreen shares reserve feature period       10 years    
Percentage of fully diluted shares of common stock       5.00%    
Number of additional shares authorized (in shares) 9,378,902          
Maximum percentage of share reserve, outstanding diluted stock       15.00%    
Twenty Twenty One Equity Incentive Plan | Restricted stock units (RSUs)            
Class of Stock [Line Items]            
Stock compensation not yet recognized, vesting period       3 years    
Cost not yet recognized, excluding options       $ 22,400,000    
Common Stock            
Class of Stock [Line Items]            
Common stock, shares authorized (in shares)       1,010,000,000 1,010,000,000  
Common stock, par value (in dollars per share)       $ 0.0001 $ 0.0001  
Warrants issued (in shares)       1,000,000,000 1,000,000,000  
Common stock, shares outstanding (in shares)       143,034,225 141,301,569