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Collaborative Agreements (Details) - USD ($) |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | ---
May 06, 2016 | Dec. 24, 2018 | Sep. 30, 2017 | Sep. 25, 2017 | Jul. 24, 2017 | May 26, 2017 | Aug. 31, 2016 | Jul. 27, 2016 | Dec. 31, 2015 | Mar. 31, 2019 | Mar. 31, 2018 | Dec. 31, 2018 | Dec. 31, 2017
Collaborative Agreements (Textual) |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock newly issued, value |  |  |  |  |  |  |  |  |  | $ 694,219 | $ 80,000 |  |
Outstanding balance |  |  |  |  |  |  |  |  |  | 58,225 |  | $ 59,477 |
Collaborative Arrangement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements (Textual) |  |  |  |  |  |  |  |  |  |  |  |  |
Amount received from BriVision |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |
Percentage of payments under co-development agreement |  |  |  |  | 50.00% |  |  |  |  |  |  |  |
Common stock newly issued, value | $ 900,000 |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |
Licensing rights |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |
Accounts payable |  |  |  |  |  |  |  |  |  | $ 15,000,000 |  |  |
Research and development expense |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |
Co-Dev Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements (Textual) |  |  |  |  |  |  |  |  |  |  |  |  |
Amount received from BriVision |  |  | $ 3,000,000 |  |  | $ 3,000,000 |  |  |  |  |  |  | $ 450,000
Percentage of payments under co-development agreement |  |  |  |  |  | 50.00% |  |  |  |  |  |  |
Company cash payments |  |  | $ 3,000,000 |  |  | $ 3,000,000 |  |  |  |  |  |  |
Co-Dev agreement, description |  | The Company received the remaining balance of $2,550,000 in the form of newly issued shares of Rgene's Common Stock, at the price of NT$50 (approximately equivalent to $1.60 per share), for an aggregate number of 1,530,000 shares, which accounted for equity method long-term investment as of December 31, 2018. During the year ended December 31, 2018, the Company has recognized investment loss of $549. |  |  |  |  |  |  |  |  |  |  |
BHK Co-Development Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements (Textual) |  |  |  |  |  |  |  |  |  |  |  |  |
Description of payment settlement |  |  |  |  |  |  |  | Upon the signing of the BHK Co-Development Agreement: $1 million, or 10% of total payment Upon the first Investigational New Drug (IND) submission and BioLite Taiwan will deliver all data to BHK according to FDA Reviewing requirement: $1 million, or 10% of total payment At the completion of first phase II clinical trial: $1 million, or 10% of total payment At the initiation of phase III of clinical trial research: $3 million, or 30% of total payment Upon the New Drug Application (NDA) submission: $4 million, or 40% of total payment |  |  |  |  |
Upfront payments |  |  |  |  |  |  |  | $ 1,000,000 | $ 1,000,000 |  |  |  |
Percentage of payments under co-development agreement |  |  |  |  |  |  |  | 10.00% | 10.00% |  |  |  |
Milestone payments to BioLite in cash |  |  |  |  |  |  | $ 31,649,000 | $ 10,000,000 |  |  |  |  |
Common stock newly issued, value |  |  |  |  |  |  | $ 1,000,000 |  | $ 10,000,000 |  |  |  |
Milestone payments royalty percentage |  |  |  |  |  |  | 12.00% |  |  |  |  |  |
Collaborative Agreements, description |  |  |  |  |  |  |  |  | The Company recognized the cash receipt in a total of NT$50 million, approximately equivalent to $1.6 million, as collaboration revenue when all research, technical, and development data was delivered to BHK. | In addition to the total of NT$50 million, approximately equivalent to $1.60 million, BioLite Taiwan is entitled to receive 50% of the future net licensing income or net sales profit. As of March 31, 2019 and 2018, the Company has not earned the royalty under the BHK Collaborative Agreements. |  |  |

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