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v3.25.1

Collaborative Agreements (Details) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1 Months Ended | 3 Months Ended | 11 Months Ended | 12 Months Ended |  |  |  |
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Jun. 18, 2024 USD ($) | May 23, 2024 USD ($) $ / shares shares | May 14, 2024 USD ($) $ / shares shares | May 08, 2024 USD ($) $ / shares shares | Apr. 16, 2024 USD ($) $ / shares shares | Mar. 25, 2024 USD ($) $ / shares shares | Jun. 10, 2022 USD ($) | Aug. 05, 2019 USD ($) shares | Jun. 30, 2019 USD ($) shares | Dec. 24, 2018 USD ($) $ / shares shares | Sep. 30, 2018 USD ($) | Dec. 31, 2017 USD ($) | Sep. 25, 2017 USD ($) | Aug. 15, 2017 USD ($) | Aug. 31, 2016 USD ($) | Aug. 31, 2016 TWD ($) | Dec. 31, 2015 USD ($) | May 23, 2024 USD ($) $ / shares shares | Aug. 31, 2016 TWD ($) | Mar. 31, 2025 USD ($) $ / shares shares | Dec. 31, 2015 USD ($) | Dec. 31, 2024 USD ($) $ / shares shares | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2015 USD ($) | Dec. 31, 2015 TWD ($) | Apr. 11, 2024 USD ($) $ / shares | Aug. 14, 2023 $ / shares | Jul. 01, 2022 | Jul. 27, 2021 USD ($)
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 12.00% | 12.00% |  |  |  |  |  |  |  |
Total cash |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0 |  |  | $ 50,000,000 | $ 50,000,000,000,000 |  |  |  |
Cash equivalent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,600,000 |  |  | $ 152,206 | $ 1,600,000 | $ 248,382 | $ 60,155 |  | 1,600,000 |  |  |  |  |
Additional paid-in capital |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 73,978,380 |  |  |  |  |  |  |
Cash received |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 2,000 |  |  |
Value of new shares issued |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,050,000 |  |  |  |  |  |  |
Price per share (in Dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1.87 |  | $ 1.87 |  |  |  |  |  | $ 20 |  |
Equity method long term investment (in Shares) | shares |  |  |  |  |  |  |  |  |  |  | 1,530,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Service agreement eligibility amount |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone regulatory payment amount period |  |  |  |  |  |  |  | 3 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Loan amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 249,975
Percentage of working capital convertible loan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5.00% |  | 5.00% |  |  |  |  |  |  |  |
Fixed conversion price equal (in Dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1 |  | $ 1 |  |  |  |  |  |  |  |
Licensing fee |  |  |  |  |  |  | $ 33,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,895,556 |  |  |  |  |  |
FEYE stock (in Dollars per share) | $ / shares |  |  |  |  |  |  | $ 6 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone regulatory payment amount |  | $ 3,500,000 |  |  |  |  | $ 3,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of royalties of net sales |  |  |  |  |  |  | 5.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Recognized revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 296,000 |  |  |  |  |  |  |  |
Recognized revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 200,000 |  | $ 200,000 |  |  |  |  |  |  |  |
BHK Co-Development Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Description of collaborative agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | On July 27, 2016, BioLite Taiwan and BHK agreed to amend the payment terms of the milestone payment in an aggregate amount of $10 million based on the following schedule: ● Upon the signing of the BHK Co-Development Agreement: $1 million, or 10% of total payment ● Upon the first Investigational New Drug (IND) submission and BioLite Taiwan will deliver all data to BHK according to FDA Reviewing requirement: $1 million, or 10% of total payment ● At the completion of first phase II clinical trial: $1 million, or 10% of total payment ● At the initiation of phase III of clinical trial research: $3 million, or 30% of total payment ● Upon the New Drug Application (NDA) submission: $4 million, or 40% of total payment |  | On July 27, 2016, BioLite Taiwan and BHK agreed to amend the payment terms of the milestone payment in an aggregate amount of $10 million based on the following schedule: ● Upon the signing of the BHK Co-Development Agreement: $1 million, or 10% of total payment ● Upon the first Investigational New Drug (IND) submission and BioLite Taiwan will deliver all data to BHK according to FDA Reviewing requirement: $1 million, or 10% of total payment ● At the completion of first phase II clinical trial: $1 million, or 10% of total payment ● At the initiation of phase III of clinical trial research: $3 million, or 30% of total payment ● Upon the New Drug Application (NDA) submission: $4 million, or 40% of total payment |  |  |  |  |  |  |  |
Non-refundable upfront cash payment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,000,000 |  |  |  | $ 1,000,000 |  |  |  |  |  |  |  |  |
Data and development percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10.00% |  |  |  | 10.00% |  |  |  |  |  |  |  |  |
Total cash amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,000,000 |  | $ 10,000,000 |  |  |  | $ 10,000,000 |  |  |  |  |  |  |  |  |
Licensing rights |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 31,649,000 |  |  | $ 31,649,000 |  |  |  |  |  |  |  |  |  |  |
Co-Dev Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Data and development percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 50.00% |  | 50.00% |  |  |  |  |  |  |  |
Cash amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Addition cash payment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  | $ 3,000,000 |  |  |  |  |  |  |  |
Additional paid-in capital |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash received |  |  |  |  |  |  |  |  |  |  |  |  | 450,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Data and development percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 50.00% |  | 50.00% |  |  |  |  |  |  |  |
Total cash amount |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licensing rights |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  | $ 3,000,000 |  |  |  |  |  |  |  |
Research and development expense |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
BioFirst Corporation Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in Shares) | shares |  |  |  |  |  |  |  |  | 41,470 | 42,857 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock consideration |  |  |  |  |  |  |  |  | $ 2,902,911 | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
ForSeeCon Eye Corporation [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licensing agreement |  | $ 100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
BioLite Taiwan [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total cash |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 50,000,000 |  |  |  |  |  |  |  |  | $ 50,000,000,000,000 |  |  |  |
Cash equivalent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,600,000 |  |  |  | $ 1,600,000 |  |  |  | $ 1,600,000 |  |  |  |  |
Net sales profit, percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 50.00% |  |  |  |  |  |  |  | 50.00% | 50.00% |  |  |  |
Collaborative agreement with ForSeeCon Eye Corporation [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment |  |  |  |  |  |  | $ 30,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares paid (in Shares) | shares |  |  |  |  |  |  | 5,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares received (in Shares) | shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  | 5,000,000 |  |  |  |  |  |  |  |
OncoX BiopPharma, Inc [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty percentage |  |  | 5.00% | 5.00% | 5.00% | 5.00% |  |  |  |  |  |  |  |  |  |  |  |  | 5.00% |  |  |  |  |  |  |  |  |  |  |  |
Price per share (in Dollars per share) | $ / shares |  |  | $ 5 | $ 5 | $ 5 | $ 5 |  |  |  |  |  |  |  |  |  |  |  |  | $ 5 |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in Shares) | shares |  |  | 1,250,000 | 1,250,000 | 1,250,000 | 1,250,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration paid |  |  | $ 6,250,000 | $ 6,250,000 | $ 6,250,000 | $ 6,250,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional milestone payment in cash |  |  | $ 625,000 | $ 625,000 | $ 625,000 | $ 625,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares received (in Shares) | shares |  |  | 1,250,000 | 1,250,000 | 1,250,000 |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,250,000 |  | 1,250,000 |  | 1,250,000 |  |  |  |  |  |  |  |
Percentage of develop and commercialize |  |  | 50.00% | 50.00% | 50.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licensing fees |  |  | $ 100,000 | $ 100,000 | $ 100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 100,000 |  |  |  |  |  |  |  |  |  |  |  |
Rgene Corporation [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Value of new shares issued |  |  |  |  |  |  |  |  |  |  | $ 2,550,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of note fully converted |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 37.00% |  | 26.65% | 26.65% |  |  |  |  |  |  |
Loan amount |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,000,000 |  | $ 1,000,000 |  |  |  |  |  |  |  |
Ownership percentage |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 12.80% |
Convertible loan |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000 |  |  |  |  |  |  |  |  |  |
Rgene Corporation [Member] | Co-Dev Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of note fully converted |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 6.40% |  | 6.40% |  |  |  |  |  |  |  |
Rgene Corporation [Member] | Service Agreements [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of note fully converted |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 26.65% |  | 31.62% |  |  |  |  |  |  |  |
Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Value of new shares issued | [1] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 300 |  |  |  |  |  |  |
Price per share (in Dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  | $ 50 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.0001 |  |  |
Common Stock [Member] | YuanGene Corporation [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Price per share (in Dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  | $ 1.6 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common Stock [Member] | Rgene Studies [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of note fully converted |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 20.00% |  | 20.00% |  |  |  |  |  |  |  |
[1] | Prior period results have been adjusted to reflect the 1-for-10 reverse stock split effected on July 25, 2023.

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