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v3.25.1

Commitments and Contingencies (Details Narrative) | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Oct. 25, 2019 | Dec. 31, 2024 USD ($) | Dec. 31, 2024 EUR (€) | Dec. 31, 2023 USD ($) | Dec. 31, 2024 EUR (€)
Grant Repyable |  | $ 422,221 |  |  |
future research and collaboration commitments |  | 1,120,518 |  |  |
Long-term debt payable |  | 4,813,069 |  |  |
Accrued compensation expense |  | 536,535 |  |  |
Royalty Payment |  | 0 |  | $ 1,369 |
Operating Lease Right of Use Obligations [Member] |  |  |  |  |
Operating Lease Right-of-use liabilities |  | 632,441 |  |  |
Operating Lease Right-of-use Assets |  | 599,816 |  |  |
Operating Lease Liabilities |  | 250,048 |  |  |
Operating Lease Expense |  | 247,390 |  |  |
Short Term Lease Costs |  | $ 49,988 |  |  |
Tamu [Member] |  |  |  |  |
Debt conversion, Converted instrument, Rate | 7.50% |  |  |  |
Equity interest in Volition Vet |  | 12.50% | 12.50% |  |
Equity Interest | 12.50% |  |  |  |
Additional interest | 5.00% |  |  |  |
Two Thousand Twenty Two [Member] | Univercity Of Texas MD [Member] |  |  |  |  |
Collaborative Obligations Amount Due |  | $ 277,092 |  |  |
Additional Cost Of Company |  | 449,406 |  |  |
August Two Thousand Twenty Three [Member] | Guy's and St Thomas' NHS Foundation Trust [Member] |  |  |  |  |
Collaborative Obligations Amount Due |  | 162,609 |  |  |
Additional Cost Of Company |  | 162,609 |  |  |
Cost |  | 162,338 |  |  |
July Thirty One Thousand Twenty Three [Member] | Xenetic Biosciences Inc and CLS Therapeutics [Member] |  |  |  |  |
Collaborative Obligations Amount Due |  | 26,142 |  |  |
Additional Cost Of Company |  | 107,589 |  |  |
Cost |  | 81,447 |  |  |
January 2024 [Member] | Xenetic Biosciences Inc and CLS Therapeutics [Member] |  |  |  |  |
Collaborative Obligations Amount Due |  | 89,370 |  |  |
Cost |  | 134,055 |  |  |
Managing Director's Agreement [Member] |  |  |  |  |
Royalty Payment |  | $ 113,856 |  |  |
Royality |  | 6.00% | 6.00% |  |
Namur Invest [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2020 [Member] |  |  |  |  |
Loan Agreement Term |  | 10 years | 10 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 830,000 |  |
Fixed Interest Rate |  | 4.00% |  |  | 4.00%
Maturity Date |  | March 2031 | March 2031 |  |
Debt Agreement amount | € |  |  |  |  | € 556,828
Total Long-term Debt |  | $ 576,345 |  |  |
Namur Invest One [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2022 [Member] |  |  |  |  |
Loan Agreement Term |  | 4 years | 4 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 500,000 |  |
Fixed Interest Rate |  | 5.45% |  |  | 5.45%
Maturity Date |  | December 2027 | December 2027 |  |
Principal Balance Payable |  | $ 398,497 |  |  |
Agreement Under Amount | € |  |  | € 500,000 |  |
Namur Invest Two [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2022 [Member] |  |  |  |  |
Loan Agreement Term |  | 4 years | 4 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 1,000,000 |  |
Fixed Interest Rate |  | 6.00% |  |  | 6.00%
Maturity Date |  | July 2026 | July 2026 |  |
Principal Balance Payable |  | $ 495,160 |  |  |
Agreement Under Amount | € |  |  | € 1,000,000 |  |
ING [Member] | Long-term Debt [Member] | In 2016 [Member] |  |  |  |  |
Maturity Date |  | May 2031 | May 2031 |  |
Fixed Interest Rate On Lease |  | 2.62% |  |  | 2.62%
Lease Payable |  | $ 375,075 |  |  |
ING [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2016 [Member] |  |  |  |  |
Loan Agreement Term |  | 15 years | 15 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 270,000 |  |
Fixed Interest Rate |  | 2.62% |  |  | 2.62%
Maturity Date |  | December 2031 | December 2031 |  |
Principal Balance Payable |  | $ 145,654 |  |  |
Walloon Region Government [Member] | In 2010 [Member] |  |  |  |  |
Repayment Of Grants | € |  |  |  |  | € 314,406
Other income | € |  |  | € 733,614 |  |
Terms Of Agreement Description |  | it is due to pay a 6% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €314,406 and the 6% royalty on revenue, is twice the amount of funding received | it is due to pay a 6% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €314,406 and the 6% royalty on revenue, is twice the amount of funding received |  |
Amount Repayable |  | $ 25,876 |  |  |
Grant Receivable | € |  |  |  |  | 1,048,020
Walloon Region Government [Member] | In 2018 [Member] | Colorectal Cancer Research Agreement [Member] |  |  |  |  |
Repayment Of Grants | € |  |  |  |  | 181,500
Terms Of Agreement Description |  | it is due to pay a 3.53% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €181,500 and the 3.53% royalty on revenue, is equal to the amount of funding received | it is due to pay a 3.53% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €181,500 and the 3.53% royalty on revenue, is equal to the amount of funding received |  |
Amount Repayable |  | $ 84,114 |  |  |
Grant Receivable | € |  |  |  |  | 605,000
Grant Repaid By Installments |  | over 12 years | over 12 years |  |
Walloon Region Government [Member] | In 2020 [Member] |  |  |  |  |
Repayment Of Grants | € |  |  |  |  | 148,500
Terms Of Agreement Description |  | it is due to pay a 2.89% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €148,500 and the 2.89% royalty on revenue, is equal to the amount of funding received | it is due to pay a 2.89% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €148,500 and the 2.89% royalty on revenue, is equal to the amount of funding received |  |
Amount Repayable |  | $ 82,363 |  |  |
Grant Receivable | € |  |  |  |  | 495,000
Grant Repaid By Installments |  | over 10 years | over 10 years |  |
Walloon Region Government [Member] | In 2020 [Member] | Colorectal Cancer Research Agreement [Member] |  |  |  |  |
Repayment Of Grants | € |  |  |  |  | 278,830
Terms Of Agreement Description |  | it is due to pay a 4.34% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €278,830 and the 4.34% royalty on revenue, is equal to the amount of funding received | it is due to pay a 4.34% royalty on such revenue to the Walloon Region. The maximum amount payable to the Walloon Region, in respect of the aggregate of the amount repayable of €278,830 and the 4.34% royalty on revenue, is equal to the amount of funding received |  |
Amount Repayable |  | $ 229,868 |  |  |
Grant Receivable | € |  |  |  |  | € 929,433
Grant Repaid By Installments |  | over 15 years | over 15 years |  |
SOFINEX [Member] | Long-term Debt [Member] | Loan Agreement [Member] | November 23, 2021 [Member] |  |  |  |  |
Loan Agreement Term |  | 3 years 5 months 30 days | 3 years 5 months 30 days |  |
Repayment Of Long-term Loan Amount | € |  |  | € 450,000 |  |
Fixed Interest Rate |  | 5.00% |  |  | 5.00%
Maturity Date |  | June 2025 | June 2025 |  |
Principal Balance Payable |  | $ 116,443 |  |  |
Agreement Under Amount | € |  |  | € 450,000 |  |
SOFINEX [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2017 [Member] |  |  |  |  |
Loan Agreement Term |  | 7 years | 7 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 1,000,000 |  |
Fixed Interest Rate |  | 4.50% |  |  | 4.50%
Maturity Date |  | September 2024 | September 2024 |  |
Total Long-term Debt |  | $ 51,753 |  |  |
University of Taiwan [Member] | Clinical Study Research Agreement [Member] | In 2018 [Member] |  |  |  |  |
Collaborative Obligations Amount Due |  | 510,000 |  |  |
Collaborative Obligations Amount |  | $ 2,550,000 |  |  |
Lease Agreement Expire Period |  | 3 years | 3 years |  |
Namur Invest Three [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2023 [Member] |  |  |  |  |
Loan Agreement Term |  | 4 years | 4 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 400,000 |  |
Fixed Interest Rate |  | 7.00% |  |  | 7.00%
Maturity Date |  | June 2027 | June 2027 |  |
Principal Balance Payable |  | $ 360,883 |  |  |
Agreement Under Amount | € |  |  | € 400,000 |  |
Wallonie Enterprendre [Member] | Long-term Debt [Member] | Loan Agreement [Member] | In 2023 [Member] |  |  |  |  |
Loan Agreement Term |  | 5 years | 5 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 2,500,000 |  |
Fixed Interest Rate |  | 7.68% |  |  | 7.68%
Maturity Date |  | December 2028 | December 2028 |  |
Principal Balance Payable |  | $ 2,070,100 |  |  |
Agreement Under Amount | € |  |  | € 1,500,000 |  |
Namur Invest Four [Member] | Long-term Debt [Member] | Loan Agreement [Member] |  |  |  |  |
Loan Agreement Term |  | 4 years | 4 years |  |
Repayment Of Long-term Loan Amount | € |  |  | € 577,975 |  |
Fixed Interest Rate |  | 7.00% |  |  | 7.00%
Maturity Date |  | September 2028 | September 2028 |  |
Principal Balance Payable |  | $ 598,234 |  |  |
Agreement Under Amount | € |  |  | € 577,975 |  |
Restricted Stock Units [Member] |  |  |  |  |
Recognized total compensation expense |  | 1,439,767 |  | $ 527,940 |
RSU Vested in 2023 |  | 516,039 |  |  |
RSU Vested in 2024 |  | 395,788 |  |  |
Unrecognized compensation expense |  | 115,142 |  |  |
Restricted Stock Units [Member] | One |  |  |  |  |
Recognized total compensation expense |  | 494,812 |  |  |
RSU Vested in 2023 |  | 0 |  |  |
RSU Vested in 2024 |  | 80,175 |  |  |
Unrecognized compensation expense |  | $ 205,730 |  |  |

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