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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Fair Values of Stock Options Granted and Assumptions used in Black-Scholes Model

The estimated fair values of stock options granted, and the assumptions used for the Black-Scholes option pricing model were as follows:

 

 

 

 

Year ended December 31,

 

 

 

2021

 

 

2020

 

 

2019

 

Estimated fair values of stock options granted

 

$

3.61

 

 

$

3.24

 

 

$

10.18

 

Assumptions:

 

 

 

 

 

 

 

 

 

Risk-free interest rate

 

0.6% - 1.2%

 

 

0.3% - 1.7%

 

 

1.7% - 2.5%

 

Expected volatility

 

80.1% - 91.0%

 

 

77.4% - 81.2%

 

 

52.6% - 78.9%

 

Expected term (in years)

 

5.5 - 6.5

 

 

6.0 - 10.0

 

 

6.8 - 10.0

 

Summary of Stock Option Activity

Information on stock option activity is as follows:

 

 

 

 

 

Options
Exercisable

 

 

Weighted-
Average
Exercise
Price Per
Share

 

 

Options
Outstanding

 

 

Weighted-
Average
Exercise
Price Per
Share

 

Balance as of December 31, 2020

 

 

2,347,665

 

 

$

10.15

 

 

 

4,621,173

 

 

$

10.30

 

Granted

 

 

 

 

 

 

 

 

774,959

 

 

 

5.20

 

Exercised

 

 

 

 

 

 

 

 

(61,372

)

 

 

3.70

 

Forfeited or expired

 

 

 

 

 

 

 

 

(676,335

)

 

 

10.75

 

Balance as of December 31, 2021

 

 

2,789,110

 

 

$

10.23

 

 

 

4,658,425

 

 

$

9.47

 

Schedule of Net Cash Proceeds from Exercise of Stock Options Less Shares Used for Minimum Withholding Taxes and Intrinsic Value of Options Exercised

Net cash proceeds from the exercise of stock options less shares used for minimum withholding taxes and the intrinsic value of options exercised were as follows:

 

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Net cash proceeds

 

$

227

 

 

$

212

 

 

$

344

 

Intrinsic value of options exercised

 

$

344

 

 

$

179

 

 

$

905

 

Summary of Activity of Restricted Stock Units Information on restricted stock unit activity is as follows:

 

 

 

 

Number of
Restricted Stock
Units Outstanding

 

 

Weighted-
Average
Grant Date Fair
Value

 

Unvested balance at December 31, 2020

 

 

547,807

 

 

$

9.49

 

Granted

 

 

406,981

 

 

 

4.59

 

Vested

 

 

(193,857

)

 

 

7.68

 

Cancelled

 

 

(189,628

)

 

 

10.91

 

Unvested balance at December 31, 2021

 

 

571,303

 

 

$

6.15

 

Summary of Grant Date Fair Value of Restricted Stock Unit Awards Vested

The total grant-date fair value of restricted stock unit awards that vested was as follows:

 

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Grant-date fair value

 

$

1,489

 

 

$

3,122

 

 

$

3,141

 

Schedule of Weighted Average Grant Date Fair Value of Restricted Stock Units Issued

Information on the weighted average grant date fair value of restricted stock units issued was as follows:

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Weighted average grant date fair value

 

$

4.59

 

 

$

6.54

 

 

$

12.48

 

Summary of Stock-Based Compensation Granted As Deemed Dividends

The Company accounts for stock-based compensation awards granted to employees of Cellectis as deemed dividends. The Company recorded deemed dividends as follows:

 

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Deemed dividends from grants to Cellectis employees

 

$

(289

)

 

$

1,168

 

 

$

1,358

 

2021 Grant  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Fair Values of Performance Stock Units Granted and Assumptions used in Monte Carlo Simulation Pricing Model The estimated fair values of performance stock units granted in 2021, and the assumptions used were as follows:

Estimated fair values of performance stock units granted:

 

 

 

At least $12 per share

 

$

2.16

 

At least $15 per share

 

$

1.89

 

At least $20 per share

 

$

1.55

 

Assumptions:

 

 

 

Expected term (in years)

 

 

3.0

 

Expected volatility

 

 

90.0

%

Risk-free interest rate

 

 

0.4

%

2019 Grant  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Fair Values of Performance Stock Units Granted and Assumptions used in Monte Carlo Simulation Pricing Model

The estimated fair values of performance stock units granted, and the assumptions used were as follows:

 

 

Estimated fair values of performance stock units granted

 

$

7.06

 

Assumptions:

 

 

 

Expected term (in years)

 

3.0

 

Expected volatility

 

 

75.0

%

Risk-free interest rate

 

 

1.71

%

Stock Options [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Stock-based Compensation Expense

Stock-based compensation expense related to stock option awards was as follows:

 

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Stock-based compensation expenses

 

$

1,850

 

 

$

3,371

 

 

$

6,035

 

Restricted Stock Units [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Stock-based Compensation Expense

Stock-based compensation expense related to restricted stock units was as follows:

 

 

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Stock-based compensation expenses

 

$

224

 

 

$

1,155

 

 

$

2,910

 

Performance Stock Units [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Stock-based Compensation Expense

Stock-based compensation expense related to performance stock units is as follows:

 

 

Year ended December 31,

 

In Thousands

 

2021

 

 

2020

 

 

2019

 

Stock-based compensation expenses

 

$

16

 

 

$

445

 

 

$

225