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Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Feb. 23, 2022
Oct. 20, 2020
Jan. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Equity, Class of Treasury Stock [Line Items]            
Preferred stock share authorized       50,000,000.0    
Preferred stock share par value       $ 0.0001    
Net proceeds from issuance of common stock and exercise of overallotment       $ 4,139 $ 14,037  
Repurchase of Common Stock           $ 800
Common stock, shares issued       38,874,146 37,165,196  
Proceeds from common stock issuance       $ 4,380 $ 15,000 $ 0
ATM Facility [Member]            
Equity, Class of Treasury Stock [Line Items]            
Aggregate common stock offering value       $ 50,000    
Common stock, shares issued       1,400,000    
Proceeds from common stock issuance       $ 3,900    
Subsequent Event [Member]            
Equity, Class of Treasury Stock [Line Items]            
Common stock, issued and sold 3,880,000          
Net proceeds from issuance of common stock and exercise of overallotment $ 10,000          
After deduction of underwriting discounts and estimated other offering expenses $ 900          
Subsequent Event [Member] | ATM Facility [Member]            
Equity, Class of Treasury Stock [Line Items]            
Proceeds from common stock issuance     $ 200      
Subsequent Event [Member] | Pre-funded Warrants [Member] | Maximum [Member]            
Equity, Class of Treasury Stock [Line Items]            
Warrants issued (in shares) 3,880,000          
Subsequent Event [Member] | Common Warrants [Member] | Maximum [Member]            
Equity, Class of Treasury Stock [Line Items]            
Warrants issued (in shares) 7,760,000          
Follow-on Public Offering [Member]            
Equity, Class of Treasury Stock [Line Items]            
Common stock, issued and sold   3,750,000        
Common stock issued price per share   $ 4.00        
Net proceeds from issuance of common stock and exercise of overallotment   $ 14,000        
Underwriting discounts and commissions   $ 1,000        
Follow-on Public Offering [Member] | Subsequent Event [Member]            
Equity, Class of Treasury Stock [Line Items]            
Common stock, issued and sold 3,880,000          
Common stock issued price per share $ 1.41          
Net proceeds from issuance of common stock and exercise of overallotment $ 10,000          
After deduction of underwriting discounts and estimated other offering expenses $ 900          
Follow-on Public Offering [Member] | Subsequent Event [Member] | Pre-funded Warrants [Member] | Maximum [Member]            
Equity, Class of Treasury Stock [Line Items]            
Warrants issued (in shares) 3,880,000          
Follow-on Public Offering [Member] | Subsequent Event [Member] | Common Warrants [Member] | Maximum [Member]            
Equity, Class of Treasury Stock [Line Items]            
Warrants issued (in shares) 7,760,000          
Follow-on Public Offering [Member] | Cellectis [Member]            
Equity, Class of Treasury Stock [Line Items]            
Common stock, issued and sold   1,250,000     1,250,000  
Common stock issued price per share         $ 4.00  
Net proceeds from issuance of common stock and exercise of overallotment   $ 5,000        
Outstanding obligation paid to parent   $ 14,000