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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Operating activities
Net loss	$ (29,199)	$ (44,836)	$ (39,612)
Adjustments to reconcile net loss to net cash used by operating activities:
Gain upon extinguishment of Payroll Protection Program Loan	(1,528)	0	0
Depreciation and amortization	2,338	1,869	1,607
Stock-based compensation	2,090	4,971	9,175
Changes in operating assets and liabilities:
Accounts receivable	4,887	(3,765)	(1,122)
Due to/from related parties	(594)	(211)	(882)
Inventory	1,383	1,211	(2,594)
Prepaid expenses and other current assets	3,331	(3,122)	493
Accounts payable	(360)	(148)	259
Accrued expenses	(2,542)	347	537
Accrued compensation	572	(231)	876
Other	811	243	(688)
Net cash used by operating activities	(18,811)	(43,672)	(31,951)
Investing activities
Sales and (purchases) of short-term investments, net	11,698	(11,698)	0
Purchases of land, buildings, and equipment	(497)	(1,786)	(2,969)
Net cash provided (used) by investing activities	11,201	(13,484)	(2,969)
Financing activities
Proceeds from common stock issuance	4,380	15,000	0
Costs incurred related to the issuance of stock	(501)	(963)	0
Proceeds from Payroll Protection Program loan	0	1,518	0
Repayments of financing lease obligations	(364)	(360)	(275)
Proceeds from the exercise of stock options	227	212	344
Costs incurred related to shares withheld for net settlement	0	0	(813)
Proceeds from sale and leaseback of land, buildings, and equipment	0	0	414
Net cash provided (used) by financing activities	3,742	15,407	(330)
Net decrease in cash, cash equivalents, and restricted cash	(3,868)	(41,749)	(35,250)
Cash, cash equivalents and restricted cash - beginning of period	18,289	60,038	95,288
Cash, cash equivalents and restricted cash - end of period	$ 14,421	$ 18,289	$ 60,038

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