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STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) | Total | Common Stock | Additional Paid-In Capital | Accumulated Deficit
--- | --- | --- | --- | ---
Balance, shares at Sep. 30, 2018 |  | 28,034,487 |  |
Balance, amount at Sep. 30, 2018 | $ 916 | $ 280,346 | $ 331,312,184 | $ (331,591,614)
Warrant exercises, shares |  | 298,682 |  |
Warrant exercises, amount | 649,753 | $ 2,987 | 646,766 |
401(k) contributions paid in common stock, shares |  | 12,279 |  |
401(k) contributions paid in common stock, amount | 35,241 | $ 123 | 35,118 | 0
Stock issued to nonemployees for service, shares |  | 62,784 |  |
Stock issued to nonemployees for service, amount | 202,380 | $ 628 | 201,752 | 0
Shares returned for settlement of clinical research costs, shares |  | (564,905) |  |
Shares returned for settlement of clinical research costs, amount | 0 | $ (5,649) | 5,649 | 0
Equity based compensation - employees, shares |  | 0 |  |
Equity based compensation - employees, amount | 573,660 | 0 | 573,660 | 0
Net income | 1,245,902 | $ 0 | 0 | 1,245,902
Balance, shares at Dec. 31, 2018 |  | 27,843,327 |  |
Balance, amount at Dec. 31, 2018 | 2,707,852 | $ 278,435 | 332,775,129 | (330,345,712)
Balance, shares at Sep. 30, 2018 |  | 28,034,487 |  |
Balance, amount at Sep. 30, 2018 | 916 | $ 280,346 | 331,312,184 | (331,591,614)
Net income | $ (17,286,547) |  |  |
Option exercises, shares | 42,770 |  |  |
Balance, shares at Jun. 30, 2019 |  | 34,066,914 |  |
Balance, amount at Jun. 30, 2019 | $ 1,146,304 | $ 340,669 | 349,683,796 | (348,878,161)
Balance, shares at Dec. 31, 2018 |  | 27,843,327 |  |
Balance, amount at Dec. 31, 2018 | 2,707,852 | $ 278,435 | 332,775,129 | (330,345,712)
Warrant exercises, shares |  | 1,523,933 |  |
Warrant exercises, amount | 2,655,634 | $ 15,239 | 2,640,395 | 0
401(k) contributions paid in common stock, shares |  | 10,419 |  |
401(k) contributions paid in common stock, amount | 36,883 | $ 104 | 36,779 | 0
Stock issued to nonemployees for service, shares |  | 77,449 |  |
Stock issued to nonemployees for service, amount | 225,629 | $ 774 | 224,855 | 0
Shares returned for settlement of clinical research costs, shares |  | 500,000 |  |
Shares returned for settlement of clinical research costs, amount | 1,290,000 | $ 5,000 | 1,285,000 | 0
Equity based compensation - employees, shares |  | (3,500) |  |
Equity based compensation - employees, amount | 530,830 | (35) | 530,865 | 0
Net income | (6,447,681) | 0 | 0 | (6,447,681)
Share issuance costs | (43,625) | $ 0 | (43,625) | 0
Balance, shares at Mar. 31, 2019 |  | 29,951,628 |  |
Balance, amount at Mar. 31, 2019 | 955,522 | $ 299,517 | 337,449,398 | (336,793,393)
Warrant exercises, shares |  | 4,014,109 |  |
Warrant exercises, amount | 10,252,821 | $ 40,141 | 10,212,680 | 0
401(k) contributions paid in common stock, shares |  | 4,339 |  |
401(k) contributions paid in common stock, amount | 36,361 | $ 43 | 36,318 | 0
Stock issued to nonemployees for service, shares |  | 20,825 |  |
Stock issued to nonemployees for service, amount | 140,270 | $ 208 | 140,062 | 0
Equity based compensation - employees, amount | 1,521,821 | (40) | 1,521,861 | 0
Net income | (12,084,768) | 0 | 0 | (12,084,768)
Share issuance costs | (8,010) | $ 0 | (8,010) | 0
Purchase of stock by officers and directors, shares |  | 37,243 |  |
Purchase of stock by officers and directors, amount | $ 234,997 | $ 372 | 234,625 | 0
Option exercises, shares | 42,770 | 42,770 |  |
Option exercises, amount | $ 97,290 | $ 428 | 96,862 | 0
Balance, shares at Jun. 30, 2019 |  | 34,066,914 |  |
Balance, amount at Jun. 30, 2019 | 1,146,304 | $ 340,669 | 349,683,796 | (348,878,161)
Balance, shares at Sep. 30, 2019 |  | 35,231,776 |  |
Balance, amount at Sep. 30, 2019 | 5,133,667 | $ 352,318 | 358,507,603 | (353,726,254)
Warrant exercises, shares |  | 132,900 |  |
Warrant exercises, amount | 297,101 | $ 1,329 | 295,772 | 0
401(k) contributions paid in common stock, shares |  | 4,474 |  |
401(k) contributions paid in common stock, amount | 40,937 | $ 45 | 40,892 | 0
Stock issued to nonemployees for service, shares |  | 15,819 |  |
Stock issued to nonemployees for service, amount | 84,447 | $ 158 | 84,289 | 0
Equity based compensation - employees, shares |  | 0 |  |
Net income | (5,531,360) | 0 | 0 | (5,531,360)
Share issuance costs | (92,150) | $ 0 | (92,150) | 0
Adoption of new accounting standard | 2,146,195 |  |  | 2,146,195
Issuance of common stock, shares |  | 606,395 |  |
Issuance of common stock, amount | 5,050,003 | $ 6,064 | 5,043,939 | 0
Equity based compensation - employees, amount | 1,800,225 | $ 0 | 1,800,225 |
Purchase of stock by officer, shares |  | 3,725 |  |
Purchase of stock by officer, amount | 25,000 | $ 37 | 24,963 | 0
Balance, shares at Dec. 31, 2019 |  | 35,995,089 |  |
Balance, amount at Dec. 31, 2019 | 8,954,065 | $ 359,951 | 365,705,533 | (357,111,419)
Balance, shares at Sep. 30, 2019 |  | 35,231,776 |  |
Balance, amount at Sep. 30, 2019 | 5,133,667 | $ 352,318 | 358,507,603 | (353,726,254)
Net income | $ (24,876,157) |  |  |
Option exercises, shares | 94,199 |  |  |
Balance, shares at Jun. 30, 2020 |  | 38,522,236 |  |
Balance, amount at Jun. 30, 2020 | $ 20,888,291 | $ 385,223 | 396,959,284 | (376,456,216)
Balance, shares at Dec. 31, 2019 |  | 35,995,089 |  |
Balance, amount at Dec. 31, 2019 | 8,954,065 | $ 359,951 | 365,705,533 | (357,111,419)
Warrant exercises, shares |  | 562,100 |  |
Warrant exercises, amount | 4,318,706 | $ 5,621 | 4,313,085 | 0
401(k) contributions paid in common stock, shares |  | 3,376 |  |
401(k) contributions paid in common stock, amount | 38,959 | $ 34 | 38,925 | 0
Stock issued to nonemployees for service, shares |  | 17,120 |  |
Stock issued to nonemployees for service, amount | 235,024 | $ 171 | 234,853 | 0
Equity based compensation - employees, shares |  | 0 |  |
Net income | (9,067,818) | 0 | 0 | (9,067,818)
Share issuance costs | (199,372) | $ 0 | (199,372) | 0
Purchase of stock by officers and directors, shares |  | 16,787 |  |
Option exercises, shares |  | 20,480 |  |
Option exercises, amount | 49,898 | $ 205 | 49,693 | 0
Equity based compensation - employees, amount | 1,780,979 | $ 0 | 1,780,979 | 0
Proceeds from the sale of common stock, shares |  | 721,459 |  |
Proceeds from the sale of common stock, amount | 7,867,629 | $ 7,215 | 7,860,414 | 0
Purchase of stock by officers and directors, amount | 159,990 | $ 168 | 159,822 | 0
Balance, shares at Mar. 31, 2020 |  | 37,336,411 |  |
Balance, amount at Mar. 31, 2020 | 14,138,060 | $ 373,365 | 379,943,932 | (366,179,237)
Warrant exercises, shares |  | 849,845 |  |
Warrant exercises, amount | 10,156,275 | $ 8,498 | 10,147,777 | 0
401(k) contributions paid in common stock, shares |  | 2,875 |  |
401(k) contributions paid in common stock, amount | 42,895 | $ 29 | 42,866 | 0
Stock issued to nonemployees for service, shares |  | 14,811 |  |
Stock issued to nonemployees for service, amount | 205,381 | $ 148 | 205,233 | 0
Net income | (10,276,979) | 0 | 0 | (10,276,979)
Share issuance costs | $ (418,497) | $ 0 | (418,497) | 0
Option exercises, shares | 73,719 | 73,719 |  |
Option exercises, amount | $ 276,415 | $ 737 | 275,678 | 0
Equity based compensation - employees, amount | 3,109,127 | $ 0 | 3,109,127 | 0
Proceeds from the sale of common stock, shares |  | 94,575 |  |
Proceeds from the sale of common stock, amount | 1,074,807 | $ 946 | 1,073,861 | 0
Shares issued for settlement of clinical research costs, shares |  | 150,000 |  |
Shares issued for settlement of clinical research costs, amount | 1,769,500 | $ 1,500 | 1,768,000 | 0
Modification of warrants, amount | 5,554 | 0 | 5,554 | 0
Warrant issuances, amount | 805,753 | $ 0 | 805,753 | 0
Balance, shares at Jun. 30, 2020 |  | 38,522,236 |  |
Balance, amount at Jun. 30, 2020 | $ 20,888,291 | $ 385,223 | $ 396,959,284 | $ (376,456,216)

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