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Note 4 - Investment in Wanchun Pharma - Schedule of Equity Method Investment (Details) - USD ($)
Jul. 20, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Less: net assets of Wanchun Pharma (including cash of $1,256)   $ (14,908,000) $ (10,970,000)  
Wanchun Pharma [Member]        
Acquisition cost $ 2,400,000      
Less: negative equity investment in Wanchun Pharma (239,000)     $ (196,000)
Less: net assets of Wanchun Pharma (including cash of $1,256) (1,347,000)      
Excess cost allocated to patent of Plinabulin and charged to expenses $ 814,000