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v3.8.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Cash flows from operating activities: |  |  |
Net loss | $ (96,388) | $ (12,545) | $ (8,052)
Adjustments to reconcile net loss to cash used in operating activities: |  |  |
Excess cost for acquisition of an equity investee |  |  | 814
Net loss on equity method investment |  |  | 44
Imputed interest |  |  | 532
Depreciation expenses | 32 | 18 | 10
Share-based compensation | 22,683 |  |
Research and Development Expenses Settled by Shares Issuance | 42,259 |  |
Loss on disposal of property and equipment |  |  | 27
Changes in assets and liabilities: |  |  |
Advances to suppliers | (726) | (710) | (73)
Prepaid expenses and other current assets | 96 | (334) | (22)
Other noncurrent assets | (240) | (121) |
Accounts payable | 2,935 | 144 | 94
Due to related parties | (210) | (222) | (168)
Accrued expenses | 699 | (102) | 210
Other current liabilities | 64 | 174 | 14
Net cash used in operating activities | (28,796) | (13,698) | (6,570)
Cash flows from investing activities: |  |  |
Acquisitions of property and equipment | (76) | (64) | (40)
Loans to related parties |  |  | (861)
Cash obtained from acquisition of an equity investee |  |  | 1,256
Purchase of short-term investments | (3,074) |  |
Net cash provided by (used in) investing activities | (3,150) | (64) | 355
Cash flows from financing activities: |  |  |
Proceeds from issuance of ordinary shares | 50,505 | 15,250 | 16,000
Proceeds from a third party loan |  |  | 1,000
Proceeds from loans due to related parties |  |  | 1,273
Repayment of loans due to related parties |  |  | (402)
Cash distribution to equity owner in the Internal Restructuring |  |  | (1,201)
Payment of initial public offering costs | (2,783) | (537) |
Net cash provided by financing activities | 47,722 | 14,713 | 16,670
Effect of foreign exchange rate changes | 18 | (85) | (26)
Net increase in cash and cash equivalents | 15,794 | 866 | 10,429
Cash at beginning of year | 11,687 | 10,821 | 392
Cash at end of year | 27,481 | 11,687 | 10,821
Non-cash activities: |  |  |
Ordinary shares issued to acquire Wanchun Pharma |  |  | 2,400
Deemed contribution through the Internal Restructuring |  |  | 9,393
Initial public offering costs accrued in accrued expenses |  | 1,324 |
Net settlement of related party loans |  |  | 1,800
Research and development expense settled by share issuance | $ 42,259 |  |

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- Definition The cash outflow for the payment of a long-term borrowing made from a related party where one party can exercise control or significant influence over another party; including affiliates, owners or officers and their immediate families, pension trusts, and so forth. Alternate caption: Payments for Advances from Affiliates. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition The fair value of stock issued in noncash financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4332-108586 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4304-108586 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=98513485&loc=d3e4313-108586 + Details
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