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Note 8 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Notes Tables

Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]

		Year Ended December 31,
		2019				2020				2021
			$				$				$
Cayman Islands			3,843				3,805				5,652
U.S.			17,251				33,266				34,318
PRC			5,586				5,912				6,368
BVI			13,568				20,873				18,336
Australia			85				(35	)			(36	)
Loss before income tax			40,333				63,821				64,638

Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]

		Year Ended December 31,
		2019				2020				2021
			$				$				$
Current income tax			-				-				3,570
Deferred income tax			-				-				-
Income tax expenses			-				-				3,570

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

		Year Ended December 31,
		2019				2020				2021
			$				$				$
Loss before income tax			40,333				63,821				64,638
Expected income tax benefit			8,470				13,403				13,574
Tax rate difference			(3,425	)			(4,653	)			(3,796	)
Non-deductible expenses			(5,228	)			(688	)			(788	)
Research tax credits			2,360				641				1,096
Non-taxable income			-				120				21
Tax preference			-				-				3,755
Others			(99	)			68				(262	)
Change in valuation allowance			(2,078	)			(8,891	)			(17,170	)
Total income tax expenses			-				-				(3,570	)

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		December 31,
		2020				2021
			$				$
Deferred tax assets:
Net operating loss carryforward			18,034				24,211
Deferral of tax deduction of R&D expenses			5,674				6,757
Share-based compensation			1,768				1,482
Deferred revenue							9,510
Research tax credits			3,002				4,063
Operating lease liabilities			452				422
Accruals and reserves			5				11
Total deferred tax assets			28,935				46,456
Deferred tax liabilities:
Unrealized gain			-				(37	)
Depreciation			-				(254	)
Operating lease right-of-use assets			(473	)			(420	)
Total deferred tax liabilities			(473	)			(711	)
Total gross deferred tax assets			28,462				45,745
Less: valuation allowance			(28,462	)			(45,745	)
Net deferred tax assets			-				-

Summary of Income Tax Contingencies [Table Text Block]

		Year Ended December 31,
		2019				2020				2021
			$				$				$
Beginning balance, as of January 1			624				956				730
Additions based on tax positions related to prior tax years			332				-				283
Reductions based on tax positions related to prior tax years			-				(226	)			-
Additions based on tax positions related to current tax year			-				-				52
Ending balance, as of December 31
			956				730				1,065

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