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Note 15 - Forward Contract (Details Textual) - USD ($) |  |  | 1 Months Ended | 12 Months Ended | 31 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Jun. 13, 2022 | Nov. 12, 2020 | Jun. 30, 2022 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Nov. 12, 2022 | Dec. 31, 2020
Unrealized Gain (Loss) on Derivatives |  |  |  | $ (0) | $ 1,071,000 | $ 444,000 |  |
Research Collaboration and License Agreement with Eli Lilly [Member] | SEED Therapeutics Inc. [Member] |  |  |  |  |  |  |  |
Derivative Liability, Total | $ 1,237,000 |  |  |  |  |  |  | $ 278,000
Research Collaboration and License Agreement with Eli Lilly [Member] | SEED Therapeutics Inc. [Member] | Forward Liability [Member] |  |  |  |  |  |  |  |
Derivative Liability, Total |  | $ 278,000 |  |  |  |  |  |
Research Collaboration and License Agreement with Eli Lilly [Member] | SEED Therapeutics Inc. [Member] | Forward Contract [Member] |  |  |  |  |  |  |  |
Derivative Asset, Total | 1,237,000 |  |  |  | 0 | 166,000 |  |
Unrealized Gain (Loss) on Derivatives |  |  |  |  |  | $ 444,000 |  |
Gain (Loss) on Sale of Derivatives |  |  |  |  | $ 1,071,000 |  |  |
Research Collaboration and License Agreement with Eli Lilly [Member] | SEED Therapeutics Inc. [Member] | Additional Series A-2 Preferred Shares [Member] |  |  |  |  |  |  |  |
Stock Issued During Period, Value, New Issues |  |  |  |  |  |  | $ 1,990,000 |
Shares Issued, Price Per Share (in dollars per share) |  |  |  |  |  |  | $ 2.5125 |
Stock Issued During Period, Shares, New Issues (in shares) |  |  |  |  |  |  | 1,990,000 |
Research Collaboration and License Agreement with Eli Lilly [Member] | SEED Therapeutics Inc. [Member] | Series A-2 Preferred Shares [Member] |  |  |  |  |  |  |  |
Stock Issued During Period, Value, New Issues | $ 5,000,000 |  | $ 5,000,000 |  |  |  |  |
Shares Issued, Price Per Share (in dollars per share) |  | $ 2.5125 |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | 1,990,000 | 1,990,000 | 1,990,000 |  |  |  |  |

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