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Note 9 - Share-based Compensation - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Allocated Share-based Compensation Expense $ 554 $ 1,584 $ 3,152
SEED 2022 Share Incentive Plan [Member]      
Allocated Share-based Compensation Expense 216 81  
Research and Development Expense [Member]      
Allocated Share-based Compensation Expense (181) 859 901
Research and Development Expense [Member] | SEED 2022 Share Incentive Plan [Member]      
Allocated Share-based Compensation Expense 89 71  
General and Administrative Expense [Member]      
Allocated Share-based Compensation Expense 735 725 $ 2,251
General and Administrative Expense [Member] | SEED 2022 Share Incentive Plan [Member]      
Allocated Share-based Compensation Expense $ 127 $ 10