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Note 8 - Share-based Compensation - Share-based Compensation Expense (Details) - USD ($)
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
The 2017 Omnibus Incentive Plan [Member]    
Allocated Share-based Compensation Expense $ 218,000 $ 218,000
SEED 2022 Share Incentive Plan [Member]    
Allocated Share-based Compensation Expense 26 33
Research and Development Expense [Member] | The 2017 Omnibus Incentive Plan [Member]    
Allocated Share-based Compensation Expense 26,000 58,000
Research and Development Expense [Member] | SEED 2022 Share Incentive Plan [Member]    
Allocated Share-based Compensation Expense 8 16
General and Administrative Expense [Member] | The 2017 Omnibus Incentive Plan [Member]    
Allocated Share-based Compensation Expense 192,000 160,000
General and Administrative Expense [Member] | SEED 2022 Share Incentive Plan [Member]    
Allocated Share-based Compensation Expense $ 18 $ 17