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License Agreements - Additional Information (Details) - Novartis International Pharmaceutical Ltd. - USD ($) | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
May 31, 2019 | May 31, 2017 | Mar. 31, 2019 | Mar. 23, 2017
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
License agreement termination description |  |  | The agreement may be terminated by either party upon a material breach by the other party that is not cured within 60 days after written notice. The Company may terminate the agreement in its entirety or on a product-by-product or country-by-country basis with or without cause with 60 days’ prior written notice. |
Payment for development milestone |  | $ 300,000 |  |
Subsequent Event |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Payment for development milestone | $ 2,500,000 |  |  |
Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Aggregate amount payable upon satisfaction of clinical milestones |  |  |  | $ 4,300,000
Aggregate amount payable upon satisfaction of regulatory milestones for first indication approved |  |  |  | 24,000,000
Aggregate amount payable upon satisfaction of regulatory milestones for second indication approved |  |  |  | 18,000,000
Aggregate amount payable upon satisfaction of commercial milestones |  |  |  | $ 125,000,000

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- Definition License agreement milestone payments upon satisfaction of commercial milestones payable. + References No definition available. + Details
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