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Stock-Based Compensation - Schedule of Assumptions to Estimate Fair Value of Stock Options for Employees and Non-Employees Using Black-Scholes Option Pricing Model (Details) - Options Issued and Outstanding - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Employees and Directors        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term (in years) 6 years 1 month 6 days      
Expected volatility, minimum 92.40% 89.80% 92.40% 75.90%
Expected volatility, maximum 92.60% 90.60% 104.80% 90.60%
Risk-free interest rate, minimum 1.40% 2.80% 1.40% 2.40%
Risk-free interest rate, maximum 1.80% 2.90% 2.60% 2.90%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock       $ 15.45
Expected term (in years)       10 years
Expected volatility, minimum 89.70%   89.70%  
Expected volatility, maximum 90.80%   94.20%  
Risk-free interest rate, minimum 1.70%   1.70%  
Risk-free interest rate, maximum 1.90%   2.60%  
Expected dividend yield 0.00%   0.00% 0.00%
Expected volatility       77.90%
Risk-free interest rate       2.70%
Minimum [Member] | Employees and Directors        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 9.36 $ 9.03 $ 6.97 $ 8.57
Expected term (in years)   5 years 10 months 24 days 5 years 6 months 5 years 9 months 18 days
Minimum [Member] | Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 8.84   $ 6.82  
Expected term (in years) 7 years 8 months 12 days   7 years 8 months 12 days  
Maximum | Employees and Directors        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 10.66 $ 13.94 $ 10.66 $ 15.45
Expected term (in years)   6 years 1 month 6 days 6 years 1 month 6 days 6 years 7 months 6 days
Maximum | Non-employees        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Fair value of common stock $ 10.26   $ 10.26  
Expected term (in years) 9 years 6 months   10 years