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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2019
Income Tax Disclosure [Abstract] |
Schedule of Reconciliation of Income Tax Expense Computed at Statutory Federal Income Tax Rate to Income Taxes | A reconciliation of income tax expense computed at the statutory federal income tax rate to income taxes as reflected in the consolidated financial statements is as follows:
|  | Year Ended December 31, |
|  | 2019 |  |  | 2018 |  |  | 2017 |
|  | (In thousands) |
Income tax benefit at federal statutory rate |  | $ | (17,368 | ) |  | $ | (7,899 | ) |  | $ | (11,484 | )
State taxes |  |  | (5,314 | ) |  |  | (2,340 | ) |  |  | (1,011 | )
Tax credits |  |  | (2,910 | ) |  |  | (817 | ) |  |  | (222 | )
Stock-based compensation |  |  | 753 |  |  |  | 764 |  |  |  | 140 |
Federal tax rate change |  |  | — |  |  |  | — |  |  |  | 2,202 |
Change in fair value of tranche rights |  |  | — |  |  |  | 3 |  |  |  | 5,065 |
Other |  |  | 25 |  |  |  | 241 |  |  |  | — |
Change in valuation allowance |  |  | 24,850 |  |  |  | 10,074 |  |  |  | 5,310 |
Income tax expense |  | $ | 36 |  |  | $ | 26 |  |  | $ | — |
Effective tax rate |  |  | 0.0 | % |  |  | 0.0 | % |  |  | 0.0 | %
Schedule of Deferred Tax Assets and Liabilities | Deferred income taxes reflect the net tax effects of loss and credit carryforwards and temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of deferred income taxes were as follows:
|  | As of December 31, |
|  | 2019 |  |  | 2018 |
|  | (In thousands) |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating losses |  | $ | 34,938 |  |  | $ | 13,054 |
Capitalized license |  |  | 771 |  |  |  | 835 |
Research credits |  |  | 4,151 |  |  |  | 1,007 |
Accruals |  |  | 401 |  |  |  | 514 |
Stock-based compensation |  |  | 53 |  |  |  | 51 |
Net unrealized loss |  |  | — |  |  |  | 11 |
Total gross deferred tax assets |  |  | 40,314 |  |  |  | 15,472 |
Less valuation allowance |  |  | (40,221 | ) |  |  | (15,395 | )
Total deferred tax assets |  |  | 93 |  |  |  | 77 |
Deferred tax liabilities: |  |  |  |  |  |  |  |
Net unrealized gain |  |  | 13 |  |  |  | — |
Depreciation and amortization |  |  | 80 |  |  |  | 77 |
Total gross deferred tax liability |  |  | 93 |  |  |  | 77 |
Net deferred tax assets |  | $ | — |  |  | $ | — |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 + Details
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