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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2019
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Summary of Stock-Based Compensation Expense

Total stock-based compensation expense is recognized for stock-based awards granted to employees and non-employees and has been reported in the Company’s consolidated statements of operations and comprehensive loss as follows:

 

 

 

Year Ended December 31,

 

 

 

2019

 

 

2018

 

 

2017

 

 

 

(In thousands)

 

Research and development

 

$

1,542

 

 

$

1,236

 

 

$

246

 

General and administrative

 

 

2,152

 

 

 

1,557

 

 

 

224

 

Total stock-based compensation expense

 

$

3,694

 

 

$

2,793

 

 

$

470

 

Summary of Stock Option Activity

The following table summarizes stock option activity under the Plan:

 

 

 

Shares

Available for

Grant

 

 

Number of

Options

Outstanding

 

 

Weighted-

Average

Exercise

Price

per Option ($)

 

 

Weighted-

Average

Remaining

Contract

Term (Years)

 

 

Aggregate

Intrinsic

Value ($)

 

 

 

(In thousands)

 

Outstanding, December 31, 2018

 

 

1,350,582

 

 

 

1,122,677

 

 

 

11.63

 

 

 

9.22

 

 

 

 

 

Shares reserved for issuance

 

 

1,122,213

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Options granted

 

 

(1,896,527

)

 

 

1,896,527

 

 

 

6.28

 

 

 

 

 

 

 

 

 

Restricted stock units granted

 

 

(813,335

)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Options exercised

 

 

 

 

 

(7,029

)

 

 

0.79

 

 

 

 

 

 

 

 

 

Options forfeited

 

 

449,375

 

 

 

(449,375

)

 

 

10.77

 

 

 

 

 

 

 

 

 

Outstanding, December 31, 2019

 

 

212,308

 

 

 

2,562,800

 

 

 

7.85

 

 

 

8.84

 

 

 

200

 

Exercisable, December 31, 2019

 

 

 

 

 

 

461,150

 

 

 

11.40

 

 

 

7.06

 

 

 

37

 

Vested and expected to vest, December 31, 2019

 

 

 

 

 

 

2,562,800

 

 

 

7.85

 

 

 

8.84

 

 

 

200

 

 

Schedule of Assumptions to Estimate Fair Value of Stock Options for Employees and Non-Employees Using Black-Scholes Option Pricing Model

The fair value of stock options for employees and non-employees was estimated using a Black-Scholes option pricing model with the following assumptions:

 

 

 

Year Ended December 31,

 

 

2019

 

2018

 

2017

Employees:

 

 

 

 

 

 

Fair value of common stock

 

$1.27 - $10.66

 

$8.57 - $15.45

 

$0.79 - $9.33

Expected term (in years)

 

5.5 - 6.1

 

5.8 - 6.2

 

5.9 - 6.2

Expected volatility

 

92.0% - 104.9%

 

75.9% - 90.6%

 

74.4% - 74.5%

Risk-free interest rate

 

1.4% - 2.6%

 

2.4% - 3.1%

 

1.9% - 2.2%

Expected dividend yield

 

0.0%

 

0.0%

 

0.0%

Non-employees:

 

 

 

 

 

 

Fair value of common stock

 

$1.23 - $10.26

 

$8.62 - $15.45

 

$0.79 - $10.28

Expected term (in years)

 

7.4 - 10.0

 

8.4 - 10.0

 

9.4 - 10.0

Expected volatility

 

89.7% - 99.5%

 

78.0% - 91.2%

 

74.6% - 77.0%

Risk-free interest rate

 

1.7% - 2.8%

 

2.7% - 3.1%

 

2.3% - 2.4%

Expected dividend yield

 

0.0%

 

0.0%

 

0.0%

Summary of Restricted Stock Activity

The summary of restricted stock activity and related information follows:

 

 

 

Number of

Restricted

Shares

Outstanding

 

Unvested shares — December 31, 2018

 

 

1,000

 

Vested

 

 

(1,000

)

Unvested shares — December 31, 2019

 

 

 

 

Summary of Restricted Stock Units Activity

The summary of restricted stock unit activity and related information follows:

 

 

 

Number of

Restricted

Stock Units

Outstanding

 

Unvested shares — December 31, 2018

 

 

24,960

 

Granted

 

 

813,335

 

Vested

 

 

(9,360

)

Unvested shares — December 31, 2019

 

 

828,935