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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating activities:      
Net loss $ (82,739) $ (37,614) $ (33,778)
Adjustments to reconcile net loss to net cash used in operating activities:      
Accretion on marketable securities (1,020) (673)  
Depreciation and amortization expense 125 80 5
Loss on disposal of property and equipment 53    
Stock-based compensation expense 3,694 2,793 470
Change in fair value of tranche liability     14,896
Expense related to acquisition of intellectual property     3,157
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets (274) (630) (876)
Accounts payable 3,727 1,597 1,392
Accrued liabilities 2,756 (1,022) 3,749
Other liabilities (4) 19  
Net cash used in operating activities (73,682) (35,450) (10,985)
Investing activities:      
Purchases of property and equipment (271) (362) (44)
Maturities of marketable securities 141,500 7,500  
Purchase of marketable securities (97,103) (107,854)  
Net cash provided by (used in) investing activities 44,126 (100,716) (44)
Financing activities:      
Proceeds from public offering, net of issuance costs 49,747 90,908  
Proceeds from at-the-market offering, net of issuance costs 6,716    
Deferred offering costs   (970) (568)
Taxes paid related to net share settlement of restricted stock units (20)    
Proceeds from exercise of stock options 6 5  
Net cash provided by financing activities 56,449 89,943 64,378
Net increase (decrease) in cash, cash equivalents and restricted cash 26,893 (46,223) 53,349
Cash, cash equivalents and restricted cash at beginning of period 7,126 53,349  
Cash, cash equivalents and restricted cash at end of period 34,019 7,126 53,349
Supplemental disclosure of non-cash investing and financing activities:      
Cash paid for income taxes $ 62    
Conversion of redeemable convertible preferred stock into common stock   $ 81,620  
Series A Redeemable Convertible Preferred Stock      
Financing activities:      
Proceeds from issuance of redeemable convertible preferred stock     25,000
Series B Redeemable Convertible Preferred Stock      
Financing activities:      
Proceeds from issuance of redeemable convertible preferred stock     $ 39,946