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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2019
Income Tax Disclosure [Abstract]  
Schedule of Reconciliation of Income Tax Expense Computed at Statutory Federal Income Tax Rate to Income Taxes

A reconciliation of income tax expense computed at the statutory federal income tax rate to income taxes as reflected in the consolidated financial statements is as follows:

 

     Year Ended December 31,  
     2019     2018     2017  
     (In thousands)  

Income tax benefit at federal statutory rate

   $ (17,368   $ (7,899   $ (11,484

State taxes

     (5,314     (2,340     (1,011

Tax credits

     (2,910     (817     (222

Stock-based compensation

     753       764       140  

Federal tax rate change

     —         —         2,202  

Change in fair value of tranche rights

     —         3       5,065  

Other

     25       241       —    

Change in valuation allowance

     24,850       10,074       5,310  
  

 

 

   

 

 

   

 

 

 

Income tax expense

   $ 36     $ 26     $ —    
  

 

 

   

 

 

   

 

 

 

Effective tax rate

     0.0     0.0     0.0
  

 

 

   

 

 

   

 

 

 
Schedule of Deferred Tax Assets and Liabilities

Deferred income taxes reflect the net tax effects of loss and credit carryforwards and temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of deferred income taxes were as follows:

 

     As of December 31,  
     2019      2018  
     (In thousands)  

Deferred tax assets:

     

Net operating losses

   $ 34,938      $ 13,054  

Capitalized license

     771        835  

Research credits

     4,151        1,007  

Accruals

     401        514  

Stock-based compensation

     53        51  

Net unrealized loss

     —          11  
  

 

 

    

 

 

 

Total gross deferred tax assets

     40,314        15,472  

Less valuation allowance

     (40,221      (15,395
  

 

 

    

 

 

 

Total deferred tax assets

     93        77  
  

 

 

    

 

 

 

Deferred tax liabilities:

     

Net unrealized gain

     13        —    

Depreciation and amortization

     80        77  
  

 

 

    

 

 

 

Total gross deferred tax liability

     93        77  
  

 

 

    

 

 

 

Net deferred tax assets

   $ —        $ —