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Commitment and Contingencies - Additional Information (Detail) - USD ($)
 1 Months Ended 12 Months Ended
Apr. 30, 2019
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Mar. 31, 2020
Aug. 01, 2019
Long-term Purchase Commitment [Line Items]            
Estimated litigation liability   $ 0     $ 0  
Amended lease term from the date of relocation           7 years
Amended base rent per year of the relocation premises $ 600,000          
Percentage increase in operating lease base rent 2.00%          
Letters of Credit issued amount $ 200,000          
Lease payments   500,000 $ 300,000 $ 0    
Novartis International Pharmaceutical Ltd. | Maximum            
Long-term Purchase Commitment [Line Items]            
Aggregate amount payable upon satisfaction of clinical milestones   1,500,000        
Aggregate amount payable upon satisfaction of regulatory milestones for first indication approved   24,000,000        
Aggregate amount payable upon satisfaction of regulatory milestones for second indication approved   18,000,000        
Aggregate amount payable upon satisfaction of commercial milestones   $ 125,000,000