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Segment Reporting - Summary of Company's segment information (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
ExternalProgramExpensesForProductCandidatesAbstract            
Total External Program Expenses For Product Candidates $ 9,289   $ 6,850   $ 14,091 $ 12,464
Non Program Specific Expenses [1] 2,089   3,788   4,764 6,322
Personnel-related expenses (including non-cash stock-based compensation) [2] 12,840   15,738   27,633 31,773
Depreciation 1,655   1,602   3,335 3,253
Professional services and consulting fees 2,156   1,241   4,420 2,600
Facilities And Infrastructure Expenses 2,379   1,984   4,605 4,095
Other Segment Expense [3] 1,984   1,646   3,429 3,212
Interest income (1,398)   (2,999)   (3,081) (5,917)
Other Expense, Net 223   51   235 115
Income tax provision 0   0   0 0
Segment net loss 31,217 $ 28,214 29,901 $ 28,016 59,431 57,917
ADI Zero Zero One Expenses [Member]            
ExternalProgramExpensesForProductCandidatesAbstract            
Total External Program Expenses For Product Candidates 4,484   5,729   7,852 10,314
ADI Two Seven Zero Expenses [Member]            
ExternalProgramExpensesForProductCandidatesAbstract            
Total External Program Expenses For Product Candidates 4,104   1,035   5,470 1,963
ADI Two One Two Expenses [Member]            
ExternalProgramExpensesForProductCandidatesAbstract            
Total External Program Expenses For Product Candidates 701   0   769 0
Other Programs [Member]            
ExternalProgramExpensesForProductCandidatesAbstract            
Total External Program Expenses For Product Candidates [4] $ 0   $ 86   $ 0 $ 187
[1] Relates to platform research and development expenses which are not attributed to specific programs.
[2] Relates to personnel-related expenses including non-cash stock-based compensation for the three months ended June 30, 2025 and 2024 of $2.9 million and $6.0 million, respectively, and the six months ended June 30, 2025 and 2024 of $6.1 million and $11.7 million, respectively.
[3] Relates to other expenses primarily for software subscriptions and licenses, office expenses, travel and entertainment, director compensation and recruiting fees.
[4] Relates to programs that have been discontinued or are currently in the research stage.