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Stock Based Compensation - Summary of Stock Options Outstanding (Details) - $ / shares | 3 Months Ended | 12 Months Ended
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Mar. 31, 2019 | Mar. 31, 2018 | Dec. 31, 2018 | Dec. 31, 2017
STOCK-BASED COMPENSATION |  |  |  |
Number of stock options outstanding, Beginning of period | 19,170 | 5,723 | 5,723 | 110,828
Number of stock options outstanding, Granted |  |  | 812,689 | 189,164
Number of stock options outstanding, Expired | (280) | (112) | (140,374) | (13,818)
Number of stock options outstanding, Canceled or forfeited |  |  |  |
Number of stock options outstanding, End of period | 18,890 | 5,611 | 19,170 | 5,723
Number of stock options Exercisable, End of period | 18,890 | 1,828 | 958,489 | 97,010
Weighted average exercise price, Beginning of period | $ 79.78 | $ 276.50 | $ 276.50 | $ 18.24
Weighted average exercise price, Granted |  |  | 0.98 | 1.40
Weighted average exercise price, Expired | 179.68 | 624.00 | 5.97 | 50.88
Weighted average exercise price, Canceled or forfeited |  |  |  |
Weighted average exercise price, End of period | 78.21 | 269.50 | 79.78 | 276.50
Weighted average exercise price Exercisable, End of period | $ 78.21 | $ 682.50 | $ 1.60 | $ 13.59

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- Definition The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Number of options or other stock instruments for which the right to exercise has lapsed under the terms of the plan agreements. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(4) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(3) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Gross number of share options (or share units) granted during the period. + References No definition available. + Details
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- Definition Number of options outstanding, including both vested and non-vested options. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Weighted average price at which grantees could have acquired the underlying shares with respect to stock options of the plan that expired. + References No definition available. + Details
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