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Equity Incentive Plans - Stock-based compensation (Details) - USD ($)
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Equity Incentive Plan    
Total stock-based compensation $ 190,424 $ 565,432
Research and development    
Equity Incentive Plan    
Total stock-based compensation 182,237 166,869
General and administrative    
Equity Incentive Plan    
Total stock-based compensation $ 8,187 $ 398,563