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Summary of Significant Accounting Policies - Going Concern and Segment Information (Details)
$ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
segment
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
segment
Dec. 31, 2020
USD ($)
Accounting Policies [Abstract]        
Cash and cash equivalents $ 50,370   $ 128,318 $ 60,495
Accumulated deficit (434,863)   (379,889) (333,200)
Net cash used in operating activities (71,336) $ (26,718) (42,591) (39,271)
Net income (loss) $ (54,974) $ (30,591) $ (46,689) $ (37,713)
Number of operating segments | segment 1   1