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Income Taxes - Narrative (Details) - USD ($)
 3 Months Ended 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2024
Dec. 31, 2023
Income Taxes [Line Items]        
Foreign earnings repatriated $ 0 $ 0 $ 0 $ 0
Deferred income taxes recognized 0 0 0 0
Income tax expense     $ 0 $ 0
Effective tax rate     0.00% 0.00%
Statutory tax rate     21.00% 21.00%
Tax losses and credits carried forward 456,014,000 395,590,000 $ 456,014,000 $ 395,590,000
Net operating loss carryforwards, subject to expiration 148,511,000 144,588,000 148,511,000 144,588,000
Net operating loss carryforwards, not subject to expiration 272,391,000 215,891,000 272,391,000 215,891,000
Deferred tax assets valuation allowance 205,566,000 171,223,000 205,566,000 171,223,000
Deferred income tax     0 0
Accrued interest and penalties     0 0
Domestic | United States        
Income Taxes [Line Items]        
Tax losses and credits carried forward 376,507,000 321,743,000 376,507,000 321,743,000
State and local        
Income Taxes [Line Items]        
Tax losses and credits carried forward 34,019,000 30,011,000 34,019,000 30,011,000
Foreign        
Income Taxes [Line Items]        
Tax losses and credits carried forward 45,456,000 43,805,000 45,456,000 43,805,000
R&D tax credits        
Income Taxes [Line Items]        
Tax credits $ 35,111,000 $ 35,147,000 $ 35,111,000 $ 35,147,000