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Share-based compensation - Schedule of Stock Options Activity (Detail) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2019	Dec. 31, 2018
Number of options
Beginning balance (in shares)	112,000
Granted (in shares)	2,030,000
Ending balance (in shares)	2,142,000	112,000
Options vested and expected to vest (in shares)	2,142,000
Options exercisable (in shares)	112,000
Weighted average exercise price per share
Beginning balance (in usd per share)	$ 13.98
Granted (in usd per share)	4.64
Ending balance (in usd per share)	5.13	$ 13.98
Options vested and expected to vest (in usd per share)	5.13
Options exercisable (in usd per share)	$ 13.98
Weighted average remaining contractual term, options outstanding	9 years 6 months	2 years 10 months
Options vested and expected to vest	9 years 6 months
Weighted average remaining contractual term, options exercisable	2 years 7 months
Aggregate intrinsic value, beginning balance	$ 0
Aggregate intrinsic value, ending balance	2,009	$ 0
Aggregate intrinsic value, options vested and expected to vest	2,009
Aggregate intrinsic value, options exercisable	$ 19

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- Definition

The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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Gross number of share options (or share units) granted during the period.

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Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Amount by which current fair value of underlying stock exceeds exercise price of fully vested and expected to vest exercisable or convertible options. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Number of fully vested and expected to vest options outstanding that can be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Weighted average remaining contractual term for vested portions of options outstanding and currently exercisable or convertible, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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