<SEC-DOCUMENT>0001493152-25-021317.txt : 20251107
<SEC-HEADER>0001493152-25-021317.hdr.sgml : 20251107
<ACCEPTANCE-DATETIME>20251107171017
ACCESSION NUMBER:		0001493152-25-021317
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251107
DATE AS OF CHANGE:		20251107

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			JUPITER NEUROSCIENCES, INC.
		CENTRAL INDEX KEY:			0001679628
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				474828381
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41265
		FILM NUMBER:		251463554

	BUSINESS ADDRESS:	
		STREET 1:		1001 NORTH US HWY 1
		STREET 2:		SUITE 504
		CITY:			JUPITER
		STATE:			FL
		ZIP:			33477
		BUSINESS PHONE:		(561) 406-6154

	MAIL ADDRESS:	
		STREET 1:		1001 NORTH US HWY 1
		STREET 2:		SUITE 504
		CITY:			JUPITER
		STATE:			FL
		ZIP:			33477

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Jupiter Orphan Therapeutics, Inc.
		DATE OF NAME CHANGE:	20160713
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STATES</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 18pt"><B>SECURITIES
AND EXCHANGE COMMISSION</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 12pt"><B>Washington,
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 18pt"><B>SCHEDULE
14A</B></FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B><I>Proxy
Statement Pursuant to Section 14(a) of the<BR>
Securities Exchange Act of 1934</I></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;
Preliminary Proxy Statement</FONT></P>

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Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))</FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: justify">&#9744;<FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">
Definitive Proxy Statement</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0.25in; text-align: justify">&#9746; <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Definitive
Additional Materials</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#160;</FONT></P>

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Soliciting Material under &#167;240.14a-12</FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 18pt"><B>JUPITER
NEUROSCIENCES, INC.</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0pt 0pt 0; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Name
of Registrant as Specified In Its Charter)</FONT></P>

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No fee required</FONT></P>

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<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>JUPITER NEUROSCIENCES, INC.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>1001 North US HWY 1, Suite 504</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Jupiter, FL 33477</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Telephone: (561) 406-6154</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Supplement to the Proxy
Statement for the Annual Meeting of Stockholders to be held on </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>December 19, 2025 at 10:00 A.M. Eastern
Time</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">This supplement (the &ldquo;<B>Supplement</B>&rdquo;)
amends and supplements the definitive proxy statement on Schedule 14A (the &ldquo;<B>Proxy Statement</B>&rdquo;) filed by Jupiter Neurosciences,
Inc. (the &ldquo;<B>Company</B>&rdquo;) with the Securities and Exchange Commission on November 6, 2025 in connection with the Company&rsquo;s
2025 Annual Meeting of Stockholders (the &ldquo;<B>Annual Meeting</B>&rdquo;), to be held at 10:00 A.M. (Eastern Time) on Friday,
December 19, 2025.&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The purpose of this Supplement
is to correct certain calculations in the Proxy Statement due to a scrivener&rsquo;s error. Other than these corrections, the Proxy Statement
remains unchanged, and this Supplement does not otherwise amend, supplement, or affect the Proxy Statement. From and after the date of
this Supplement, any references to the &ldquo;Proxy Statement&rdquo; are to the Proxy Statement as amended and supplemented by this Supplement.
This Supplement should be read in conjunction with the Proxy Statement and the other proxy materials previously made available to stockholders
in connection with the Annual Meeting.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">If you have already voted
your shares, you do not need to vote again unless you would like to change or revoke your prior vote on any proposal.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Corrections to the Proxy Statement</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Page 44</B>: In Proposal No. 5, the maximum
number of shares of the Company&rsquo;s common stock, par value of $0.0001 (the &ldquo;<B>Common Stock</B>&rdquo;) that the Company may
issue unless the Company obtains the requisite stockholder approval to issue shares of Common Stock in excess of the Exchange Cap to Yorkville
under the SEPA and upon conversion of the Convertible Notes in accordance with applicable Nasdaq rules is amended and restated in the
following paragraph to read as follows (corrections are marked, with new text bold and underlined, and deleted text stricken through):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in 0pt 40.5pt; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in 0pt 40.5pt; text-align: justify">Under the applicable Nasdaq rules,
in no event may the Company issue to Yorkville under the SEPA or upon conversion of the Convertible Notes, collectively, more than <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><STRIKE>6,638,088</STRIKE></FONT>
<B><U>6,855,459</U></B> shares of Common Stock, which number of shares is equal to 19.99% of the shares of Common Stock outstanding immediately
prior to the execution of the SEPA (the &ldquo;<B>Exchange Cap</B>&rdquo;), unless the Company obtains the requisite stockholder approval
to issue shares of Common Stock in excess of the Exchange Cap to Yorkville under the SEPA and upon conversion of the Convertible Notes
in accordance with applicable Nasdaq rules. At the upcoming 2025 annual meeting of the Company&rsquo;s stockholders to be held on December
19, 2025 (the &ldquo;<B>Annual Meeting</B>&rdquo;), among other things, the Company will seek the requisite stockholder approval in accordance
with Rule 5635(d) of the Nasdaq Listing Rules (in addition to the requisite stockholder approval under Nasdaq Listing Rule 5635(b)) to
issue and sell shares of Common Stock in excess of the <STRIKE>6,638,088</STRIKE> <B><U>6,855,459</U></B> share Exchange Cap referred
to above to Yorkville under the SEPA and upon conversion of the Convertible Notes. Accordingly, if such requisite stockholder approval
is obtained at the Annual Meeting, the Company would be able to issue and sell to Yorkville in Advances under the SEPA as many shares
of Common Stock as will be necessary for the Company to obtain the entire $20.0 million aggregate purchase commitment made by Yorkville
under the SEPA, which includes amounts that are used as Advance Repayments of outstanding amounts under the Convertible Notes, and as
many shares of Common Stock as will be necessary to enable Yorkville to convert all outstanding amounts under the Convertible Notes that
Yorkville elects to convert into shares of Common Stock under the terms of the Convertible Notes, in each case, without any further aggregate
share issuance limitations under Nasdaq rules. However, the <STRIKE>6,638,088</STRIKE> <B><U>6,855,459</U></B> share Exchange Cap will
continue to limit issuances and sales of Common Stock by the Company to Yorkville under the SEPA and upon conversion of the Convertible
Notes, unless and until the Company has obtained such requisite stockholder approval to issue shares of Common Stock in excess of the
Exchange Cap to Yorkville under the SEPA and upon conversion of the Convertible Notes in accordance with applicable Nasdaq rules.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in 0pt 40.5pt; text-align: justify">&nbsp;</P>

<P STYLE="text-align: center; margin-top: 0; margin-bottom: 0"></P>

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<P STYLE="text-align: center; margin-top: 0; margin-bottom: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Page 46</B>: In Proposal No. 5, the maximum
number of shares of the Company&rsquo;s Common Stock that the Company may issue unless the Company obtains the requisite stockholder approval
to issue shares of Common Stock in excess of the Exchange Cap to Yorkville under the SEPA and upon conversion of the Convertible Notes
in accordance with applicable Nasdaq rules is amended and restated in the following paragraphs to read as follows (corrections are marked,
with new text bold and underlined, and deleted text stricken through):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify">Pursuant to Nasdaq Listing Rule 5635(d), stockholder
approval is also required prior to a 20% or more of the Common Stock or 20% or more of the voting power outstanding before the issuance
at a price that is less than the Minimum Price. &ldquo;<B>Minimum Price</B>&rdquo; is defined as the lower of (i) the Nasdaq Official
Closing Price (as reflected on Nasdaq.com) immediately preceding the signing of the binding agreement; or (ii) the average Nasdaq Official
Closing Price of the Common Stock (as reflected on Nasdaq.com) for the five (5) trading days immediately preceding the signing of the
binding agreement. Shares of our Common Stock issuable upon conversion of debt instruments, such as the Convertible Notes, in such non-public
offerings are considered shares issued in such a transaction in determining whether the 20% limit has been reached. Based on the signing
of the SEPA on October 24, 2025, the applicable &ldquo;Minimum Price&rdquo; is $1.48 per share, and we are able to issue <STRIKE>6,638,088</STRIKE>
<B><U>6,855,459</U></B> shares of our Common Stock without exceeding the Exchange Cap.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.5in; text-align: justify">Until this Proposal No. 5 is approved by our
stockholders, Yorkville may not purchase more than <STRIKE>6,638,088</STRIKE> <B><U>6,855,459</U></B> of Common Stock pursuant to the
SEPA (which includes shares of Comon Stock issuable upon conversion of the Convertible Notes), representing 19.99% of the shares of Common
Stock outstanding as of the date of entry into the SEPA, which number shall be reduced, on a share-for-share basis, by the number of shares
issued or issuable pursuant to any transaction or series of transactions that may be aggregated with the SEPA under Nasdaq&rsquo;s rules
(the &ldquo;<B>Exchange Cap</B>&rdquo;). Stockholder approval of this Proposal No. 5 will constitute stockholder approval for purposes
of Nasdaq Listing Rules 5635(b) and 5635(d).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Page 47</B>: In Proposal No. 5, the percentage
reflecting the number of issued and outstanding shares at the time of the execution of the Standby Equity Purchase Agreement with YA II
PN, Ltd. is amended and restated in the following paragraph to read as follows (corrections are marked, with new text bold and underlined,
and deleted text stricken through):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">For example, if the fixed conversion priced of
the First Convertible Note were to be adjusted down to the absolute Floor Price of $0.296 under the terms of the First Convertible Note,
and the full principal amount (without adding any accrued interest or other amounts payable thereunder) under the First Convertible Note
were to be converted into shares of Common Stock at such absolute Floor Price, the number of shares issuable upon such conversion would
be 13,513,514 shares of Common Stock, or <STRIKE>40.7</STRIKE> <B><U>39.3</U></B>% of the issued and outstanding shares at the time of
the execution of the SEPA (an additional 10,846,847 shares compared to the number of shares issuable upon conversion at $1.50 per share).
Furthermore, if the fixed conversion price of the Second Convertible Note were to be adjusted down to the absolute Floor Price of $0.296
under the terms of the Second Convertible Note, and the full principal amount (without adding any accrued interest or other amounts payable
thereunder) under the Second Convertible Note were to be converted into shares of Common Stock at such absolute Floor Price, the number
of shares issuable upon such conversion would be 6,756,757 shares of Common Stock, or <STRIKE>20.3</STRIKE> <B><U>19.7</U></B>% of the
issued and outstanding shares at the time of the execution of the SEPA (an additional 5,423,424 shares compared to the number of shares
issuable upon conversion at $1.50 per share).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

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