<SEC-DOCUMENT>0001213900-18-004006.txt : 20180403
<SEC-HEADER>0001213900-18-004006.hdr.sgml : 20180403
<ACCEPTANCE-DATETIME>20180403175504
ACCESSION NUMBER:		0001213900-18-004006
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20180402
FILED AS OF DATE:		20180403
DATE AS OF CHANGE:		20180403

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Vitolo Ottavio V.
		CENTRAL INDEX KEY:			0001736257

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-55347
		FILM NUMBER:		18734905

	MAIL ADDRESS:	
		STREET 1:		71 WESTLAND AVENUE
		CITY:			NEWTON
		STATE:			MA
		ZIP:			02465

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RELMADA THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001553643
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				455401931
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		275 MADISON AVENUE, SUITE 702
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016
		BUSINESS PHONE:		646-677-3853

	MAIL ADDRESS:	
		STREET 1:		275 MADISON AVENUE, SUITE 702
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CAMP NINE, INC.
		DATE OF NAME CHANGE:	20120706
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>f3040218vitolo_relmada.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2018-04-02</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001553643</issuerCik>
        <issuerName>RELMADA THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>RLMD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001736257</rptOwnerCik>
            <rptOwnerName>Vitolo Ottavio V.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O RELMADA THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>750 THIRD AVENUE, 9TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NY</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10016</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Medical Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Warrants to purchase common stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.80</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2017-06-27</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2027-06-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>150000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Options to purchase common stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.88</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2018-04-02</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2028-04-02</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>300000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Warrants 100% vested on date of grant.</footnote>
        <footnote id="F2">Pursuant to the terms of the company's Amended and Restated 2013 Stock Plan, a total of 25% of the options will vest one year from the grant date, and the remaining 75% shall vest in equal increments of 6.25% per quarter of the initial option grant over the following three year period.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Ottavio Vitolo</signatureName>
        <signatureDate>2018-04-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
