Goodwill and Intangible Assets

12 Months Ended

Dec. 31, 2020

Note 7 – Goodwill and Intangible Assets

Goodwill

Changes in goodwill for the years ended December 31, 2020 and 2019 were (in thousands):


Balance at January 1, 2019	$	14,204
Attributable to acquisition of Oncimmune, Ltd.		827
Balance at December 31 2019	$	15,031

Balance at December 31, 2020	$	15,031

Intangible Assets, Net

Intangible assets consist of the following (in thousands):

	December 31, 2020							December 31, 2019
	Cost		Accumulated Amortization			Net Carrying Value		Cost		Accumulated Amortization			Net Carrying Value
Intangible assets subject to amortization
Patents	$	1,474	$	(494	)	$	980	$	1,245	$	(411	)	$	834
Purchased technology		16,900		(4,694	)		12,206		16,900		(2,817	)		14,083
Purchase option		—		—			—		121		(17	)		104
Intangible assets not subject to amortization
Trademarks		74		—			74		71		—			71
Total	$	18,448	$	(5,188	)	$	13,260	$	18,337	$	(3,245	)	$	15,092

Amortization expense related to definite-lived intangible assets was (in thousands):

	Year ended December 31,
	2020		2019
Direct costs and expenses	$	13	$	15
Sales, marketing, general and administrative		2,051		1,959
Total	$	2,064	$	1,974

Future estimated amortization expense of intangible assets is (in thousands):

There have been no impairments of intangible assets for the twelve-month periods ended December 31, 2020 and December 31, 2019.