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Fair Value - Additional Information (Details) |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 31, 2021 USD ($) Installment $ / shares shares | Mar. 19, 2021 USD ($) | Jan. 31, 2022 USD ($) | Sep. 30, 2020 | Jan. 31, 2016 USD ($) shares | Jun. 30, 2021 USD ($) | Dec. 31, 2021 USD ($) Installment $ / shares shares | Dec. 31, 2020 USD ($) | Dec. 31, 2018 USD ($) Installment shares | Oct. 27, 2020 shares | Feb. 28, 2018 USD ($) shares
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net change to contingent consideration |  |  |  |  |  |  | $ 1,622,000 | $ 818,000 |  |  |
Put option liability |  |  |  |  |  |  |  | 3,400,000 |  |  |
Warrants, expires period | Feb. 23, 2028 |  |  |  |  |  | Feb. 23, 2028 |  |  |  |
Estimated air value of warrants issued | $ 300,000 |  |  |  |  |  | $ 300,000 |  |  |  |
Increase in value of the warrant liability |  |  |  |  |  |  |  | 1,252,000 |  |  |
IPO |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant, exercise price | $ / shares | $ 4.46 |  |  |  |  |  | $ 4.46 |  |  |  |
Warrant issued to purchase shares | shares | 103,326 |  |  |  |  |  | 103,326 |  |  | 103,326 |
Series F Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent value rights shares | shares |  |  |  |  | 3,999 |  |  |  |  |  |
Contingent value rights |  |  |  |  | $ 500,000 |  |  |  |  |  |
Contingent value rights percentage |  |  |  |  | 0.00375% |  |  |  |  |  |
Net proceeds percentage of cash payment to the CVR holders |  |  |  |  | 15.00% |  |  |  |  |  |
Series F Preferred Stock | AVEO Oncology |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of development and regulatory costs exercised using opt-out right |  |  |  | 50.00% |  |  |  |  |  |  |
2018 Notes |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Repayments of Debt |  | $ 25,900,000 |  |  |  |  |  |  |  |  |
Estimated air value of warrants issued |  |  |  |  |  |  |  |  |  |  | $ 300,000
2018 Notes | Series G Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued to purchase shares | shares | 613,333 |  |  |  |  |  | 613,333 |  |  |  | 613,333
Warrant, exercise price | $ / shares | $ 0.75 |  |  |  |  |  | $ 0.75 |  |  |  |
Second Amendment |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Repayments of Debt | $ 20,000,000 |  |  |  |  |  |  |  |  |  |
Milestone payment | $ 4,600,000 |  |  |  |  |  |  |  |  |  |
Second Amendment | Subsequent Event |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Milestone payment |  |  | $ 4,600,000 |  |  |  |  |  |  |  |
Operating Expense |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net change to contingent consideration |  |  |  |  |  |  |  | $ 800,000 |  |  |
Operating Expense | Loss |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net change to contingent consideration |  |  |  |  |  |  | $ 1,600,000 |  |  |  |
Interest Expense |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net change to contingent consideration |  |  |  |  |  |  | $ 2,200 |  |  |  |
Integrated Diagnostics, Inc |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Business acquisition description |  |  |  |  |  |  | requires additional consideration to be paid by the Company to Indi upon attainment of a three-consecutive month |  |  |  |
Business acquisition contingent consideration gross margin target |  |  |  |  |  | $ 2,000,000.0 | $ 2,000,000.0 |  | $ 2,000,000.0 |  |
Business acquisition contingent consideration gross margin target period |  |  |  |  |  |  |  |  | 7 years |  |
Integrated Diagnostics, Inc | Common Stock |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Business acquisition description |  |  |  |  |  |  | If Indi elected to not exercise its option, the Company had 12 months to repurchase the common stock in two equal and consecutive quarterly cash installments totaling $37.0 million. |  |  |  |
Contingent consideration shares | shares |  |  |  |  |  |  |  |  | 2,520,108 |  |
Contingent consideration number of installments | Installment | 6 |  |  |  |  |  | 6 |  | 8 |  |
Contingent consideration arrangements, common shares, redemption amount |  |  |  |  |  |  | $ 4,600,000 |  | $ 37,000,000.0 |  |
Repayments of Debt |  |  |  |  |  |  | 9,300,000 |  |  |  |
Business combination contingent consideration final payment |  |  |  |  |  |  | $ 37,000,000.0 |  |  |  |
Integrated Diagnostics, Inc | Common Stock | Repurchase |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent consideration number of installments | Installment |  |  |  |  |  |  |  |  | 2 |  |
Contingent consideration cash payment |  |  |  |  |  |  |  |  | $ 37,000,000.0 |  |
Minimum |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of probabilities of contingent consideration successful achievement of specified product gross margin targets discount rates range |  |  |  |  |  |  | 11.00% |  |  |  |
Maximum |  |  |  |  |  |  |  |  |  |  |
Fair Value Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of probabilities of contingent consideration successful achievement of specified product gross margin targets discount rates range |  |  |  |  |  |  | 13.50% |  |  |  |

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