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CONSOLIDATED STATEMENTS OF LOSS AND COMPREHENSIVE LOSS - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Expenses      
General and administrative $ 15,926,103 $ 10,058,083 $ 8,407,427
External research and development fees 6,328,104 7,832,847 0
Share-based payments 7,443,930 8,052,011 12,082,930
Depreciation and amortization 4,045,523 3,900,458 1,943,048
Legal provision 0 757,829 0
Impairment of right-of-use asset 0 89,860 50,888
Total operating expenses 33,743,660 30,691,088 22,484,293
Loss from continuing operations (33,743,660) (30,691,088) (22,484,293)
Other income (1,292) (3,691) (40,454)
Finance expense 69,404 235,581 155,316
Loss (gain) on settlement of financial liability (49,792) (680,164) 18,665
Loss (gain) on change in fair value of warrants and derivative liability (682,507) (2,561,456) 2,684,436
Loss (gain) on changes in fair value of investments 858,483 770,874 8,778,707
Net loss from continuing operations (33,937,956) (28,452,232) (34,080,963)
Net loss from discontinued operations (1,347,473) (3,347,561) (5,048,557)
Net loss (35,285,429) (31,799,793) (39,129,520)
Items that may be subsequently reclassified to income (loss):      
Exchange gain (loss) on translation of foreign operations 31,815 292,573 (84,776)
Comprehensive loss $ (35,253,614) $ (31,507,220) $ (39,214,296)
Basic and diluted - continuing operations (in dollars per share) $ (0.97) $ (2.36) $ (4.83)
Basic and diluted - discontinued operations (in dollars per share) $ (0.04) $ (0.28) $ (0.72)
Weighted average number of shares outstanding – basic and diluted 34,945,210 12,043,961 7,056,245