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Acquisition of Prismic - Schedule of black scholes options pricing model (Details)
1 Months Ended 12 Months Ended
Jun. 28, 2019
Year
$ / shares
Dec. 31, 2021
$ / shares
Dec. 31, 2020
$ / shares
Dec. 31, 2019
$ / shares
Warrants [Abstract]        
Grant date share price       $ 32.16
Expected dividend yield   0.00% 0.00% 0.00%
Expected life (years)     5 years  
Annualized volatility   120.00% 117.00% 100.00%
Bottom of range        
Warrants [Abstract]        
Grant date share price   $ 2.00 $ 2.58  
Exercise price   $ 1.53 $ 3.46 $ 2.61
Risk free interest rate   0.43% 0.32% 1.41%
Expected life (years)   1 year 2 months 8 days   1 year 4 months 20 days
Annualized volatility   88.00% 118.00%  
Top of range        
Warrants [Abstract]        
Grant date share price   $ 2.04 $ 4.00  
Exercise price   $ 2.50 $ 5.80 $ 26.73
Risk free interest rate   0.46% 0.36% 1.52%
Expected life (years)   2 years   6 years 6 months 18 days
Annualized volatility   129.00% 121.00%  
Prismic Pharmaceuticals Inc. ("Prismic")        
Share Options [Abstract]        
Grant date share price $ 32.16      
Expected dividend yield 0.00%      
Annualized volatility 100.00%      
Warrants [Abstract]        
Grant date share price $ 32.16      
Expected dividend yield 0.00%      
Annualized volatility 100.00%      
Prismic Pharmaceuticals Inc. ("Prismic") | Bottom of range        
Share Options [Abstract]        
Exercise price $ 2.61      
Risk free interest rate 1.39%      
Expected life (years) | Year 0.98      
Warrants [Abstract]        
Exercise price $ 2.61      
Risk free interest rate 1.41%      
Expected life (years) 1 year 4 months 20 days      
Prismic Pharmaceuticals Inc. ("Prismic") | Top of range        
Share Options [Abstract]        
Exercise price $ 17.89      
Risk free interest rate 1.66%      
Expected life (years) | Year 16.21      
Warrants [Abstract]        
Exercise price $ 26.73      
Risk free interest rate 1.52%      
Expected life (years) 6 years 6 months 18 days