    <SEC-DOCUMENT>0001213900-21-018094-index.html : 20210329
    <SEC-HEADER>0001213900-21-018094.hdr.sgml : 20210329
    <ACCEPTANCE-DATETIME>20210329061502
    ACCESSION NUMBER:		0001213900-21-018094
    CONFORMED SUBMISSION TYPE:	S-1/A
    PUBLIC DOCUMENT COUNT:		17
    FILED AS OF DATE:		20210329
    DATE AS OF CHANGE:		20210329

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Clene Inc.
    		CENTRAL INDEX KEY:			0001822791
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-1/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-253173
    		FILM NUMBER:		21779381

    	BUSINESS ADDRESS:
    		STREET 1:		6550 SOUTH MILLROCK DRIVE, SUITE G50
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84121
    		BUSINESS PHONE:		801-676-9695

    	MAIL ADDRESS:
    		STREET 1:		6550 SOUTH MILLROCK DRIVE, SUITE G50
    		CITY:			SALT LAKE CITY
    		STATE:			UT
    		ZIP:			84121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Chelsea Worldwide Inc.
    		DATE OF NAME CHANGE:	20200827
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-1/A
    <SEQUENCE>1
    <FILENAME>fs12021a1_cleneinc.htm
    <DESCRIPTION>REGISTRATION STATEMENT
    <TEXT>
    Document 1 - file: fs12021a1_cleneinc.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.2
    <SEQUENCE>2
    <FILENAME>fs12021a1ex23-2_cleneinc.htm
    <DESCRIPTION>CONSENT OF PRICEWATERHOUSECOOPERS LLP INDEPENDENT REGISTERED ACCOUNTING FIRM FOR CLENE INC
    <TEXT>
    Document 2 - file: fs12021a1ex23-2_cleneinc.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tclenelogo.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tclenelogo.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>timage_000.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: timage_000.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>timage_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: timage_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>timage_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: timage_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>timage_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: timage_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>timage_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: timage_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>timage_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: timage_006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>timage_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: timage_007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>timage_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: timage_008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>timage_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: timage_009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>timage_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: timage_010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>timage_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: timage_011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>timage_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: timage_012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>timage_013.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: timage_013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>timage_014.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: timage_014.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>