<SEC-DOCUMENT>0001437749-23-017621-index.html : 20230616
<SEC-HEADER>0001437749-23-017621.hdr.sgml : 20230616
<ACCEPTANCE-DATETIME>20230616080132
ACCESSION NUMBER:		0001437749-23-017621
CONFORMED SUBMISSION TYPE:	S-3MEF
PUBLIC DOCUMENT COUNT:		5
<REFERENCE-462B>333-264299
FILED AS OF DATE:		20230616
DATE AS OF CHANGE:		20230616
EFFECTIVENESS DATE:		20230616

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Clene Inc.
		CENTRAL INDEX KEY:			0001822791
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				852828339
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3MEF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-272692
		FILM NUMBER:		231019386

	BUSINESS ADDRESS:	
		STREET 1:		6550 SOUTH MILLROCK DRIVE, SUITE G50
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84121
		BUSINESS PHONE:		801-676-9695

	MAIL ADDRESS:	
		STREET 1:		6550 SOUTH MILLROCK DRIVE, SUITE G50
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Chelsea Worldwide Inc.
		DATE OF NAME CHANGE:	20200827
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3MEF
<SEQUENCE>1
<FILENAME>clnn20230612_s3mef.htm
<DESCRIPTION>FORM S-3MEF
<TEXT>
Document 1 - file: clnn20230612_s3mef.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>ex_533606.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: ex_533606.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>ex_533605.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 3 - file: ex_533605.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>ex_532579.htm
<DESCRIPTION>FILING FEE TABLE
<TEXT>
Document 4 - file: ex_532579.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>hklogo35px.jpg
<TEXT>
Document 5 - file: hklogo35px.jpg

</DOCUMENT>
</SEC-DOCUMENT>