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Note 7 - Leases (Details Textual) | 1 Months Ended |  |
--- | --- | --- | ---
Sep. 30, 2022 | Feb. 28, 2022 | Sep. 30, 2021 | Mar. 31, 2024 | Dec. 31, 2023
Number of Real Estate Leases |  |  |  | 3 |
Operating Lease, Weighted Average Discount Rate, Percent |  |  |  | 9.60% | 9.60%
Operating Lease, Weighted Average Remaining Lease Term (Year) |  |  |  | 6 years 1 month 6 days | 6 years 4 months 24 days
Finance Lease, Weighted Average Discount Rate, Percent |  |  |  | 11.00% | 11.00%
Finance Lease, Weighted Average Remaining Lease Term (Year) |  |  |  | 1 month 6 days | 4 months 24 days
Lease for Laboratory Space [Member] |  |  |  |  |
Lessee, Operating Lease, Term of Contract (Year) |  | 7 years | 10 years |  |
Lessee, Operating Lease, Option To Extend Period (Year) | 5 years | 10 years | 10 years |  |
Lessee, Operating Lease, Renewal Term (Year) | 7 years |  |  |  |

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- Definition Represents option to extend period for lessee operating lease. + References No definition available. + Details
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- Definition Weighted average discount rate for finance lease calculated at point in time. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 55 -Paragraph 53 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479589/842-20-55-53 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 4 -Subparagraph (g)(4) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478964/842-20-50-4 + Details
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- Definition Weighted average remaining lease term for finance lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 55 -Paragraph 53 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479589/842-20-55-53 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 4 -Subparagraph (g)(3) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478964/842-20-50-4 + Details
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- Definition Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Subparagraph (a)(3) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478964/842-20-50-3 + Details
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